1. Unit startpage
  2. Employees
  3. Ashot Gevorgyan
Bilde av Gevorgyan, Ashot
Bilde av Gevorgyan, Ashot
Research Scientist, Chemical Synthesis and Analysis Department of Chemistry gevorgyan.ashot@uit.no

Ashot Gevorgyan

Job description

Principal Investigator

Research, Education and Administrative Work

URL to my website: https://en.uit.no/project/gevorgyan-lab  

  • Ljiljana Pavlovic, Martin Pettersen, Ashot Gevorgyan, Janakiram Vaitla, Annette Bayer, Kathrin Helen Hopmann :
    Computational and experimental insights into asymmetric Rh‐catalyzed hydrocarboxylation with CO2
    European Journal of Organic Chemistry 2020 ARKIV / PROSJEKT / FULLTEKST / DOI

    • The 50 latest publications is shown on this page. See all publications in Cristin here →

    Publications outside Cristin

    1. Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impurities
      A. Gevorgyan,* K. H. Hopmann, A. Bayer, Organometallics 2022, doi.org/10.1021/acs.organomet.1c00517.
      Highlighted in C2W popular science magazine of the Royal Netherlands Chemical Society (KNCV) as a promising new direction in green chemistry!
    2. Lipids as Versatile Solvents for Chemical Synthesis
      A. Gevorgyan,* K. H. Hopmann, A. Bayer, Green Chem. 2021, 23, 7219-7227.
      Highlighted in Chemistry World news magazine of the Royal Society of Chemistry (RSC) as a promising new direction in green chemistry!
      Highlighted in C2W popular science magazine of the Royal Netherlands Chemical Society (KNCV) as a promising new direction in green chemistry!
    3. Computational and Experimental Insights into Asymmetric Rh-Catalyzed Hydrocarboxylation with CO2
      L. Pavlovic, M. Pettersen, A. Gevorgyan, J. Vaitla, A. Bayer,* K. H. Hopmann,* Eur. J. Org. Chem. 2021, 663-670.
    4. Renewable Solvents for Palladium-Catalyzed Carbonylation Reactions
      A. Ismael, A. Gevorgyan, T. Skrydstrup, A. Bayer,* Org. Process Res. Dev. 2020, 24, 2665-2675.
    5. Formal C-H Carboxylation of Unactivated Arenes
      A. Gevorgyan,* K. H. Hopmann, A. Bayer,* Chem. Eur. J. 2020, 26, 6064-6069.
      Highlighted in Org. Chem. Highlights, as a unique concept for selective functionalization of benzenes!
    6. Exploration of New Biomass-Derived Solvents: Application to Carboxylation Reactions
      A. Gevorgyan,* K. H. Hopmann, A. Bayer,* ChemSusChem 2020, 13, 2080-2088.
    7. Mechanistic Insights into Copper-Catalyzed Carboxylations
      M. F. Obst, A. Gevorgyan, A. Bayer,* K. H. Hopmann,* Organometallics 2020, 39, 1545-1552.
    8. Cesium Fluoride-Mediated Hydrocarboxylation of Alkenes and Allenes: Scope and Mechanistic Insights
      A. Gevorgyan, M. F. Obst, Y. Guttormsen, F. Maseras, K. H. Hopmann,* A. Bayer,* Chem. Sci. 2019, 10, 10072-10078.
    9. Application of Silicon-Initiated Water Splitting for the Reduction of Organic Substrates
      A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, V. O. Iaroshenko,* ChemPlusChem 2018, 83, 375-382.
    10. Sonogashira reaction of 5-substituted 3-(prop-2-yn-1-yl)oxolan-2-ones
      T. V. Ghochikyan, M. A. Samvelyan,* A. S. Galstyan, A. Gevorgyan, G. Vardanyan, T. Grigoryan, P. Langer, Russ. J. Organ. Chem. 2017, 53:12, 1833-1839.
    11. Disilanes as oxygen scavengers and surrogates of hydrosilanes suitable for selective reduction of nitroarenes, phosphine oxides and other valuable substrates
      A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, V. O. Iaroshenko,* Org. Chem. Front. 2017, 4, 2437-2444.
    12. Synthesis of Alkynylated Dihydrofuran-2(3H)-ones as Potent and Selective Inhibitors of Tissue Non-Specific Alkaline Phosphatase
      A. Petrosyan, T. V. Ghochikyan, S. A. Ejaz, Z. Z. Mardiyan, S. U. Khan, T. Grigoryan, A. Gevorgyan, M. A. Samvelyan, A. S. Galstyan, S. Parpart, Q. Rahman, J. Iqbal, P. Langer,* ChemistrySelect 2017, 2, 5677-5683.
    13. Synthesis of 4-quinolones, benzopyran derivatives and other fused systems based on the domino ANRORC reactions of (ortho-fluoro)-3-benzoylchromones
      V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, T. Grigoryan, A. Villinger, P. Langer,* RSC Adv. 2015, 5, 28717-28724.
    14. Transition-metal-catalyzed arylation of nitroimidazoles and further transformations of manipulable nitro group
      V. O. Iaroshenko,* A. Gevorgyan, S. Mkrtchyan, K. Arakelyan, T. Grigoryan, J. Yedoyan, A. Villinger, P. Langer,* J. Org. Chem. 2015, 80, 2103-2119.
    15. Regioselective direct arylation of fused 3-nitropyridines and other nitro-substituted heteroarenes: the multipurpose nature of the nitro group as a directing group
      V. O. Iaroshenko,* A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, E. Movsisyan, A. Villinger, P. Langer,* ChemCatChem 2015, 7, 316-324.
    16. Regioselective and guided C-H activation of 4-nitropyrazoles
      V. O. Iaroshenko,* A. Gevorgyan, O. Davydova, A. Villinger, P. Langer,* J. Org. Chem. 2014, 79, 2906-2915.
      Highlighted in the ACS Select Virtual Issue  on recent discoveries that illuminate current trends and inspiring discoveries in C-H Functionalization.
    17. Efficient synthesis of novel benzo[b][1,8]naphthyridin-4(1H)-ones and pyrido[2,3-b]quinoxalin-4(1H)-ones from alkynones and primary amines
      V. O. Iaroshenko,* M. Zahid, S. Mkrtchyan, A. Gevorgyan, K. Altenburger, I. Knepper, A. Villinger, V. Y. Sosnovskikh, P. Langer, Tetrahedron 2013, 69, 2309-2318.
    18. Design, synthesis and transformation of some heteroannulated 3-aminopyridines-purine isosteres with exocyclic nitrogen atom
      V. O. Iaroshenko,* M. Vilches-Herrera, A. Gevorgyan, S. Mkrtchyan, K. Arakelyan, D. Ostrovskyi, M. S. A. Abbasi, L. Supe, A. Hakobyan, A. Villinger, D. M. Volochnyuk, A. Tolmachev, Tetrahedron 2013, 69, 1217-1228.
    19. Asymmetric synthesis of enantiomerically enriched (S)-α-aminopropionic acids containing heterocyclic side chains
      A. S. Saghyan,* G. M. Mkrtchyan, A. S. Dadayan, S. G. Petrosyan, A. V. Geolchanyan, H. M. Simonyan, A. F. Mkrtchyan, S. Mkrtchyan, A. Gevorgyan, V. O. Iaroshenko, P. Langer,* Tetrahedron: Asymmetry 2013, 24, 229-232.
    20. 2,3-Unsubstituted chromones and their enaminone precursors as versatile reagents for the synthesis of fused pyridines
      V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, M. Miliutina, A. Villinger, D. Volochnyuk, V. Y. Sosnovskikh, P. Langer,* Org. Biomol. Chem. 2012, 10, 890-894.
    21. Synthesis of heteroannulated 3-nitro- and 3-aminopyridines by cyclocondensation of electron-rich aminoheterocycles with 3-nitrochromone
      V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, M. Vilches-Herrera, D. V. Sevenard, A. Villinger, T. V. Ghochikyan, A. Saghiyan, V. Y. Sosnovskikh, P. Langer,* Tetrahedron 2012, 68, 2532-2543.
    22. Design and synthesis of condensed thienocoumarins by Suzuki-Miyaura reaction/lactonization tandem protocol
      V. O. Iaroshenko,* S. Ali, S. Mkrtchyan, A. Gevorgyan, T. M. Babar, V. Semeniuchenko, Z. Hassan, A. Villinger, P. Langer, Tetrahedron Lett. 2012, 53, 7135-7139.
    23. Asymmetric synthesis of new β-heterocyclic (S)-α-aminopropionic acids
      A. S. Saghyan,* H. M. Simonyan, L. A. Stepanyan, S. G. Ghazaryan, A. V. Geolchanyan, L. L. Manasyan, V. T. Ghochikyan, T. V. Ghochikyan, N. A. Hovhannisyan, A. Gevorgyan, V. O. Iaroshenko, P. Langer,* Tetrahedron: Asymmetry 2012, 23, 891-897.
    24. 3-Methoxalylchromone - a novel versatile reagent for the regioselective purine isostere synthesis
      S. Mkrtchyan, V. O. Iaroshenko,* S. Dudkin, A. Gevorgyan, M. Vilches-Herrera, G. Ghazaryan, D. M. Volochnyuk, D. Ostrovskyi, Z. Ahmed , A. Villinger, V. Y. Sosnovskikh, P. Langer,* Org. Biomol. Chem. 2010, 8, 5280-5284.
    25. Synthesis of chromeno[3,4-b]pyrrol-4(3H)-ones by cyclocondensation of 1,3-bis(trimethylsilyloxy)buta-1,3-dienes with 4-chloro-3-nitrocoumarin
      O. Fatunsin, V. O. Iaroshenko,* S. Dudkin, M. Shkoor, D. Volochnyuk, A. Gevorgyan, P. Langer,* Synlett 2010, 1533-1535.

    Research interests

    My research is focusing on:

    • Green chemistry
    • Homogeneous catalysis
    • Organic synthesis

    Over the past decades, homogeneous catalysis has shaped the modern organic synthesis. Many industrial processes are now based on catalytic transformations. Our mission is the design and invention of active sustainable homogeneous catalysts suitable for chemical transformations of industrial importance. 

    We have an ongoing project on the design of renewable phosphine ligands, which can be used for Pd-catalyzed cross-coupling reactions. Applications from highly motivated students to join the group for a BSc or MSc thesis in the topics of our research interests are welcome. Please contact Dr. Gevorgyan. 

    Qualified and highly motivated individuals can get support on their applications for mobility grants:

    Teaching

    2019 - present Interdisciplinary molecular sciences: from quantum mechanics to medicine (KJE-3001, for MSc and PhD students) - Co-leader, organization of seminars and production of teaching material.

    2018 - present Organometallic compounds in organic synthesis (KJE-3308/KJE-8308, for MSc and PhD students) - Co-leader, organization of lectures and seminars, production of teaching material.

    Researcher profile in Cristin
    ORCID: http://orcid.org/0000-0002-7968-6695

    Member of project

    Gevorgyan Lab    English content

    CV

    Positions - current and previous
    2021 - present Principal investigator - Dept. of Chemistry, UiT The Arctic University of Norway - Norway
    2020 - 2021 Researcher - Dept. of Chemistry, UiT The Arctic University of Norway - Norway
    2018 - 2020 Postdoctoral Fellow - Dept. of Chemistry, UiT The Arctic University of Norway - Norway
    2015 - 2018 Postdoctoral Fellow - The Center of Molecular and Macromolecular Studies, Polish Academy of Sciences in Lodz - Poland

    Education
    2015 Ph D in Chemistry ( Dr. rer. Nat. ), Supervisor: Prof. Peter Langer, Dept. of Chemistry - University of Rostock - Germany
    2011 MSc in Pharmaceutical Chemistry , Dept. of Chemistry - Yerevan State University - Armenia

    Ongoing projects
    Ligands for the Future: The First Generation of Renewable Phosphines and N-Heterocyclic Carbenes for Sustainable Catalysis .
    Research Council of Norway, Researcher Project for Young Research Talents (313462), 2021-2024.