Photo: Andreas Palmén
Annette Bayer
Head of Department; Professor, Chemical Synthesis and Analysis
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Hans-Matti Blencke,
Tor Haug
et al.:
Investigation of Tetrasubstituted Heterocycles Reveals Hydantoins as a Promising Scaffold for Development of Novel Antimicrobials with Membranolytic Properties
European Journal of Medicinal Chemistry 2023
Lisa Myrseth Hemmingsen,
Barbara Giordani,
Marianne Hagensen Paulsen,
Zeljka Vanic,
Gøril Eide Flaten,
Beatrice Vitali
et al.:
Tailored anti-biofilm activity – Liposomal delivery for mimic of small antimicrobial peptide
Susannah von Hofsten,
Manuel K Langer,
Katja Korelin,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Trude Anderssen
et al.:
Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
Frontiers in Pharmacology 30. March 2023 DOI
Susannah von Hofsten,
Marianne Hagensen Paulsen,
Synnøve Magnussen,
Dominik Ausbacher,
Mathias Kranz,
Annette Bayer
et al.:
The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Francesco Zilioli,
Tor Haug
et al.:
A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
Lianne H. E. Wieske,
Jonathan Bogaerts,
Albin A. M. Leding,
Scott Wilcox,
Anna Andersson Rasmussen,
Kinga Leszczak
et al.:
NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impurities
Marianne Hagensen Paulsen,
Magnus Engqvist,
Dominik Ausbacher,
Trude Anderssen,
Manuel K- Langer,
Tor Haug
et al.:
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Lipids as Versatile Solvents for Chemical Synthesis
Ljiljana Pavlovic,
Martin Pettersen,
Ashot Gevorgyan,
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Computational and experimental insights into asymmetric Rh‐catalyzed hydrocarboxylation with CO2
Ikenna E. Ndukwe,
Yu-hong Lam,
Sunil Kumar Pandey,
Bengt Erik Haug,
Annette Bayer,
Edward C. Sherer
et al.:
Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements
Zeeshan Muhammad,
Susann Skagseth,
Marc Boomgaren,
Sundus Akhter,
Christopher Frøhlich,
Aya Ismael
et al.:
Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases
Yngve Guttormsen,
Magnus John Espeland Fairhurst,
Sunil Kumar Pandey,
Johan Isaksson,
Bengt Erik Haug,
Annette Bayer
:
Total synthesis of phorbazole B
Aya Ismael,
Ashot Gevorgyan,
Troels Skrydstrup,
Annette Bayer
:
Renewable solvents for palladium-catalyzed carbonylation reactions
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Exploration of New Biomass-Derived Solvents: Application to Carboxylation Reactions
Ashot Gevorgyan,
Kathrin Helen Hopmann,
Annette Bayer
:
Formal C-H carboxylation of unactivated arenes
Aya Ismael,
Troels Skrydstrup,
Annette Bayer
:
Carbonylative Suzuki-Miyaura couplings of sterically hindered aryl halides: Synthesis of 2-aroylbenzoate derivatives
Ørjan Samuelsen,
Ove Alexander Høgmoen Åstrand,
Christopher Frøhlich,
Adam Heikal,
Susann Skagseth,
Trine Josefine Olsen Carlsen
et al.:
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
Marc Obst,
Ashot Gevorgyan,
Annette Bayer,
Kathrin Helen Hopmann
:
Mechanistic Insights into Copper-Catalyzed Carboxylations
Marianne Hagensen Paulsen,
Dominik Ausbacher,
Annette Bayer,
Magnus Engqvist,
Terkel Hansen,
Tor Haug
et al.:
Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and
cationic character
Ashot Gevorgyan,
Marc Obst,
Yngve Guttormsen,
Feliu Maseras,
Kathrin Helen Hopmann,
Annette Bayer
:
Caesium Fluoride-Mediated Hydrocarboxylation of Alkenes and Allenes: Scope and Mechanistic Insights
Kine Østnes Hansen,
Jeanette hammer Andersen,
Annette Bayer,
Sunil Kumar Pandey,
Marianne Lorentzen,
Kåre Bredeli Jørgensen
et al.:
Kinase chemodiversity from the Arctic: the breitfussins
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles
Janakiram Vaitla,
Annette Bayer
:
Sulfoxonium Ylide Derived Metal Carbenoids in Organic Synthesis
Magnus John E. Fairhurst,
Zeeshan Muhammad,
Bengt Erik Haug,
Annette Bayer
:
Aldol condensations on a 3-alkylidene-2,5-diketopiperazine - synthesis of two marine natural products
Sundus Ahkter,
Bjarte Aarmo Lund,
Aya Ismael,
Manuel Langer,
Johan Isaksson,
Tony Christopeit
et al.:
A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study
Ljiljana Pavlovic,
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Rhodium-Catalyzed Hydrocarboxylation: Mechanistic Analysis Reveals Unusual Transition State for Carbon–Carbon Bond Formation
Marianne Hagensen Paulsen,
Eskil Andre Karlsen,
Dominik Ausbacher,
Trude Anderssen,
Annette Bayer,
Philipp Ochtrop
et al.:
An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2-amino acids with activity
against multi-resistant bacteria
Journal of Peptide Science 2018 DOI
Janakiram Vaitla,
Kathrin Helen Hopmann,
Annette Bayer
:
Rhodium-Catalyzed Synthesis of Sulfur Ylides via in Situ Generated Iodonium Ylides
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Synthesis of Indoles and Pyrroles Utilizing Iridium Carbenes Generated from Sulfoxonium Ylides
Kine Østnes Hansen,
Johan Isaksson,
Annette Bayer,
Jostein a Johansen,
Jeanette hammer Andersen,
Espen Hansen
:
Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons
Journal of natural products 2017 DOI
Alexandra Sofia Antunes de Sousa,
Kjersti Julin,
Sybil Akua Okyerewa Obuobi,
Annette Bayer,
Mona Johannessen,
Natasa Skalko-Basnet
et al.:
Drug-loaded DNA nanoparticles against bioflms
2023
Ataur Rahman,
Manuel K Langer,
Hans-Matti Blencke,
Tor Haug,
Johanna U Ericson,
Morten B. Strøm
et al.:
Development of novel antimicrobial peptides: two classes with improved antimicrobial and antibiofilm activity
2023 PROSJEKT
Guillaume Petit,
Kine Østnes Hansen,
Jeanette Hammer Andersen,
Espen Holst Hansen,
Annette Bayer,
Bengt Erik Haug
et al.:
A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
2023
Kjersti Julin,
Annette Bayer,
Morten Bøhmer Strøm,
Mona Johannessen,
Natasa Skalko-Basnet,
Sybil Akua Okyerewa Obuobi
:
DNA Nanocarriers for improved biofilm penetration
2022
Susannah von Hofsten,
Marianne Hagensen Paulsen,
Manuel K Langer,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Annette Bayer
et al.:
A Compound Inspired by Arctic Marine Animals Kills Cancer Cells in vitro and in vivo
2022
Ataur Rahman,
Manuel Karl Langer,
Hymonti Dey,
Jonathan Hira,
Ekaterina Mishchenko,
Annette Bayer
et al.:
Novel antimicrobial and biofilm-inhibitors from marine resources
2020
Susannah von Hofsten,
Synnøve Norvoll Magnussen,
Dominik Ausbacher,
Marianne Hagensen Paulsen,
Annette Bayer,
Morten B. Strøm
et al.:
The Marine Natural Product Mimic MHP88 Shows Anticancer Activity and has the Potential to Cause Immunogenic Cell Death
2020 ARKIV
Annette Bayer,
Eldrid Borgan
:
Små hjelpestoffer kan få gammel antibiotika til å virke igjen
13. July 2020
Annette Bayer
:
Structure-based design of carbapenemase inhibitors
2019
Annette Bayer
:
Structure Based Design of Carbapenemase Inhibitors
2019
Annette Bayer
:
Towards Antibiotic Resistance Breakers. Structure-Based Design of Carbapenemase Inhibitors.
2018
Annette Bayer
:
Research in the Bayer/CHOCO group.
2018
Annette Bayer
:
Take your career in your own hands: Make a career development plan!
2018
Annette Bayer
:
Total synthesis of Breitfussin A and B.
2018
Annette Bayer
:
Structure-based design of carbapenemase inhibitors
2018
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Sulfones and Sulfoxonium Ylides in Cascade Reactions: New Approaches to Heterocycles.
2017
Janakiram Vaitla,
Annette Bayer,
Kathrin Helen Hopmann
:
Sulfones and Sulfoxonium Ylides in Cascade Reactions: New Approaches to Heterocycles.
2017
Yngve Guttormsen,
Sunil Kumar Pandey,
Bengt Erik Haug,
Annette Bayer
:
Halogenation of electron rich heterocycles: Where does it go?
2017
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Teaching
- Introductory Organic Chemistry (KJE-1002); in 2019 i implemented a major change to the pedagogical approach - now focusing on systematic understanding of reaction mechanism rather than a system based on the oxidation state of functional groups - and teaching through a flipped-classroom approach.
- Practical Organic Chemistry and Spectroscopy(KJE-1003)
- Intermediate Organic Chemistry (KJE-3301)
- Organometallic Chemistry(KJE-3308/8308)
- Nuclear Magnetic Resonance (KJE-3305/8305)
Member of research group
Member of project
REALF C318