Bilde av Hansen, Lars Uhlin
Bilde av Hansen, Lars Uhlin
Department of Medical Biology lars.uhlin-hansen@uit.no

Lars Uhlin Hansen



  • Anna Maria Wirsing, Inger-Heidi Bjerkli, Sonja Eriksson Steigen, Oddveig G Rikardsen, Synnøve Norvoll Magnussen, Beate Hegge et al.:
    Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort
    Cancers 2021 ARKIV / DOI
  • Inger-Heidi Bjerkli, Elin Synnøve Hadler-Olsen, Elisabeth Sivy Nginamau, Helene Laurvik, Tine Merete Søland, Daniela Elena Costea et al.:
    A combined histo-score based on tumor differentiation and lymphocytic infiltrate is a robust prognostic marker for mobile tongue cancer
    Virchows Archiv 30. June 2020 ARKIV / DOI
  • Sushma Pandey, Tarig Al-Hadi Osman, Sunita Sharma, Evan Michael Vallenari, Aboulghassem Shahdafar, Chin B. Pun et al.:
    Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma
    Head and Neck 2020 ARKIV / DOI
  • Inger-Heidi Bjerkli, Helene Laurvik, Elisabeth Sivy Nginamau, Tine Merete Søland, Daniela Elena Costea, Håkon Hov et al.:
    Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
    PLOS ONE 25. September 2020 ARKIV / DOI
  • Inger-Heidi Bjerkli, Olav Jetlund, Gunnhild Karevold, Åsa Karlsdottir, Ellen A. Andreassen Jaatun, Lars Uhlin-Hansen et al.:
    Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study
    PLOS ONE 2020 ARKIV / DOI
  • Sonja Eriksson Steigen, Tine Merete Søland, Elisabeth Sivy Nginamau, Helene Laurvik, Daniela Elena Costea, Anne Christine Johannessen et al.:
    Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?
    Journal of Oral Pathology & Medicine 2020 ARKIV / DOI
  • Anna Maria Wirsing, Ida Korsnes Ervik, Marit Seppola, Lars Uhlin-Hansen, Sonja Eriksson Steigen, Elin Synnøve Hadler-Olsen :
    Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carcinoma
    Modern Pathology 2018 ARKIV / DOI
  • Synnøve Magnussen, Elin Synnøve Hadler-Olsen, Daniela Elena Costea, Eli Berg, Cristiane de Albuquerque Cavalcanti Jacobsen, Bente Mortensen et al.:
    Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
    BMC Cancer 2017 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Ann Iren Solli, Anne Dragøy Hafstad, Jan-Olof Winberg, Lars Uhlin-Hansen :
    Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
    Journal of Cellular Physiology 2015 ARKIV / DOI
  • Anna Maria Wirsing, Oddveig G Rikardsen, Sonja Eriksson Steigen, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen :
    Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma
    Tumour Biology 17. September 2015 ARKIV / DOI
  • Oddveig G Rikardsen, Synnøve Magnussen, Gunbjørg Svineng, Elin Synnøve Hadler-Olsen, Lars Uhlin-Hansen, Sonja Eriksson Steigen :
    Plectin as a prognostic marker in non-metastatic oral squamous cell carcinoma
    BMC Oral Health 2015 ARKIV / DOI
  • Eystein Skjölsvik, Tor Steensrud, Øystein Dahl-Eriksen, Lars Uhlin-Hansen, Per Lunde :
    Cardiac Perforation Caused by Cement Embolus After Total Hip Replacement
    Circulation 2015 DOI
  • Emma Pirilä, Otto Väyrynen, Elias Sundquist, Kaisa Päkkilä, Pia Nyberg, Sini Nurmenniemi et al.:
    Macrophages modulate migration and invasion of human tongue squamous cell carcinoma
    PLOS ONE 2015 ARKIV / DOI
  • Anna Wirsing, Oddveig G Rikardsen, Sonja Eriksson Steigen, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen :
    Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma
    BMC Clinical Pathology 2014 ARKIV / DOI
  • Oddveig G Rikardsen, Inger-Heidi Bjerkli, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen, Sonja Eriksson Steigen :
    Clinicopathological characteristics of oral squamous cell carcinoma in Northern Norway: a retrospective study
    BMC Oral Health 2014 ARKIV / DOI
  • Synnøve Magnussen, Elin Synnøve Hadler-Olsen, Nadezhda Latysheva, Emma Pirila, Sonja Eriksson Steigen, Robert Hanes et al.:
    Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes
    PLOS ONE 2014 ARKIV / DOI
  • Synnøve Magnussen, Oddveig G Rikardsen, Elin Synnøve Hadler-Olsen, Lars Uhlin-Hansen, Sonja Eriksson Steigen, Gunbjørg Svineng :
    Urokinase Plasminogen Activator Receptor (uPAR) and Plasminogen Activator Inhibitor-1 (PAI-1) are potential predictive biomarkers in early stage Oral Squamous Cell Carcinomas (OSCC)
    PLOS ONE 07. July 2014 ARKIV / DOI
  • Nabin Malla, Eli Berg, Achilleas D. Theocharis, Gunbjørg Svineng, Lars Uhlin-Hansen, Jan-Olof Winberg :
    Invitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican
    The FEBS Journal 2013 DOI
  • Ann Iren Solli, Bodil Irene Fadnes, Jan-Olof Winberg, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen :
    Tissue- and Cell-Specific Co-localization of Intracellular Gelatinolytic Activity and Matrix Metalloproteinase 2
    Journal of Histochemistry and Cytochemistry 2013 DOI
  • Elin Synnøve Hadler-Olsen, Jan-Olof Winberg, Lars Uhlin-Hansen :
    Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets
    Tumour Biology 01. August 2013 DOI
  • Bodil Irene Fadnes, Anne Husebekk, Gunbjørg Svineng, Øystein Rekdal, Masaki Yanagishita, Svein Olav Kolset et al.:
    The proteoglycan repertoire of lymphoid cells
    Glycoconjugate Journal 2012 ARKIV / DOI
  • Bodil Irene Fadnes, Elin Synnøve Hadler-Olsen, Ingebrigt Sylte, Lars Uhlin-Hansen, Jan-Olof Winberg :
    Matrix metalloproteinase complexes and their biological significance
    Walter de Gruyter (De Gruyter) 2012 DOI
  • Nabin Malla, Eli Berg, Ugo Moens, Lars Uhlin-Hansen, Jan-Olof Winberg :
    Biosynthesis of Promatrix Metalloproteinase-9/Chondroitin Sulphate Proteoglycan Heteromer Involves a Rottlerin-Sensitive Pathway
    PLOS ONE 2011 ARKIV / DOI
  • Bodil Irene Fadnes, Lars Uhlin-Hansen, Inger Lindin, Øystein Rekdal :
    Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells
    BMC Cancer 2011 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Jan-Olof Winberg, Finn P. Reinholt, Terje Larsen, Lars Uhlin-Hansen, Trond Geir Jenssen et al.:
    Proteases in plasma and kidney of db /db mice as markers of diabetes-induced nephropathy
    ISRN Endocrinology 2011 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Hilde Ljones, Chandra Sekhar Ravuri, Ahmad Omair, Oddveig G Rikardsen, Gunbjørg Svineng et al.:
    Organ specific regulation of tumour invasiveness and gelatinolytic activity at the invasive front
    European Journal of Cancer 2011 DOI
  • Hilde Ljones, Elin Synnøve Hadler-Olsen, Synnøve Magnussen, Oddveig G Rikardsen, sonja eriksson Steigen, elisabeth Sundkvist et al.:
    S100A4 Expression in Xenograft Tumors of human carcinoma cell lines is induced by the tumor microenvironment
    American Journal of Pathology 2011 DOI
  • Elin Synnøve Hadler-Olsen, Bodil Irene Fadnes, Ingebrigt Sylte, Lars Uhlin-Hansen, Jan-Olof Winberg :
    Regulation of matrix metalloproteinase activity in health and disease
    The FEBS Journal 2011 DOI
  • Elin Synnøve Hadler-Olsen, Premasany Kanapathippillai, Eli Berg, Gunbjørg Svineng, Jan-Olof Winberg, Lars Uhlin-Hansen :
    Gelatin In Situ Zymography on Fixed, Paraffin-embedded Tissue: Zinc and Ethanol Fixation Preserve Enzyme Activity
    Journal of Histochemistry and Cytochemistry 2010 DOI
  • Elin Synnøve Hadler-Olsen, Hilde Ljones, Oddveig G Rikardsen, Sonja Eriksson Steigen, Premasany Kanapathippillai, Reidar Grenman et al.:
    Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
    Virchows Archiv 2010 ARKIV / DOI
  • Bodil Irene Fadnes, Øystein Rekdal, lars Uhlin-hansen :
    The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells
    BMC Cancer 2009 DOI
  • Nabin Malla, Eli Berg, lars Uhlin-hansen, Jan-Olof Winberg :
    Interaction of pro-matrix metalloproteinase-9/proteoglycan heteromer with gelatin and collagen
    Journal of Biological Chemistry 2008 DOI
  • Nabin Malla, Stian Sjøli, Jan-Olof Winberg, Elin Synnøve Hadler-Olsen, lars Uhlin-hansen :
    Biological and pathobiological functions of gelatinase dimers and complexes
    Connective Tissue Research 2008 DOI
  • Berit Hansen, Inger Øynebråten, Lars Uhlin-Hansen, Bård Smedsrød :
    Endocytosis and degradation of serglycin in liver sinusoidal endothelial cells
    Molecular and Cellular Biochemistry 2006
  • Katrine Holter, Henriette Willix, Lars Uhlin-Hansen :
    Rett og Slett #50: Filleristing: En ny justisskandale?
    22. February 2023 DATA
  • Lars Uhlin-Hansen :
    Ny utgave av lærebok i rettsmedisin
    Tidsskrift for Den norske legeforening 2021 DOI
  • Sushma Pandey Dhakal, Tarig A. Osman, Sunita Sharma, Lars Uhlin-Hansen, Chin Babadur Pun, Dej K. Gautam et al.:
    Oral squamous cell carcinomas expressing higher levels of S100A14 correlate with prognosis
    2019
  • Sonja Eriksson Steigen, Anna Maria Wirsing, Elin Synnøve Hadler-Olsen, Lars Uhlin-Hansen, Marit Seppola, Ida Korsnes Ervik :
    Oral cancer and high endothelial venules (HEV)
    2017
  • Anna Wirsing, Oddveig G Rikardsen, Sonja Eriksson Steigen, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen :
    Prognostic relevance of tertiary lymphoid structures in oral squamous cell carcinoma
    2014 ARKIV
  • Anna Wirsing, Elin Synnøve Hadler-Olsen, Oddveig G Rikardsen, Lars Uhlin-Hansen :
    Tertiary lymphoid organs in oral squamous cell carcinoma
    2013
  • Ann Iren Solli, Bodil Irene Fadnes, Jan-Olof Winberg, Lars Uhlin-Hansen, Elin Synnøve Hadler-Olsen :
    Intracellular MMP-2 localization and activity
    2013
  • Elin Synnøve Hadler-Olsen, Ann Iren Solli, Anne Dragøy Hafstad, Jan-Olof Winberg, Lars Uhlin-Hansen :
    Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
    2013
  • Gunbjørg Svineng, Synnøve Magnussen, Elin Synnøve Hadler-Olsen, Nadezhda Latysheva, Emma Pirila, Sonja Eriksson Steigen et al.:
    Stromal induced expression of uPAR
    2013
  • Elin Synnøve Hadler-Olsen, Ann Iren Solli, Bodil Irene Fadnes, Lars Uhlin-Hansen, Jan-Olof Winberg :
    Tissue localization of intracellular gelatinolytic activity
    The FEBS Journal 2012
  • Arne Stray-Pedersen, Sidsel Rogde, Kari Ormstad, Åshild Vege, Gerd Jorunn Delavaris, Marianne Skjerven-Martinsen et al.:
    Forensic medical examination after the July 22nd 2011 terror attack
    2012
  • Berit Myhre Dupuy, Dorota Perchla, Gunnar Markussen, Torleiv Ole Rognum, Lars Uhlin-Hansen, Ivar Skjåk Nordrum et al.:
    DNA-analysis for DVI or other identification purposes. Evaluation of the COPAN 4N6FLOQSwabs™ for collection of blood or tissue samples from deceased individuals
    2012
  • Elin Synnøve Hadler-Olsen, Chandra Sekhar Ravuri, Hilde Ljones Wetting, Oddveig G Rikardsen, sonja eriksson Steigen, Gunbjørg Svineng et al.:
    Stromal Impact on Tumor Invasiveness and Gelatinolytic Activity at the Invasive Front
    2011
  • Elin Synnøve Hadler-Olsen, Chandra Sekhar Ravuri, Hilde Ljones, Oddveig G Rikardsen, sonja eriksson Steigen, Gunbjørg Svineng et al.:
    Organ specific stromal influence on tumor invasiveness and proteolytic activity at the invasive front
    European Journal of Cancer 2010 DOI
  • Elin Synnøve Hadler-Olsen, Hilde Ljones, O Rikardsen, sonja eriksson Steigen, Jan-Olof Winberg, Gunbjørg Svineng et al.:
    Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2010
  • Nabin Malla, Eli Berg, lars Uhlin-hansen, Jan-Olof Winberg :
    Binding of promatrix metalloproteinase-9/ chondroitin sulphate proteoglycan complex to ECM
    2006

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    Research interests

    Lars Uhlin-Hansen is a professor in forensic medicine and pathology. He has a background in experimental biomedical research. In recent years his research activity has mainly been related to cancer, especially oral cancer. He is the PI for the Norwegian Oral Cancer (NOROC) study, a multidisiplinary study on oral cancer which involves the four university hospitals in Norway.

    Teaching

    Give lectures in anatomi, pathology and forensic medicine.



    Member of project