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Passbild.jpg
Department of Pharmacy manuel.k.langer@uit.no +4777644084 94086741 Tromsø Realfagbygget C418

Manuel K Langer


Doctoral Research Fellow, Chemical Synthesis and Analysis

Job description

Fouling (growth of bacteria and bigger structures on solid surfaces) on marine vessels has a huge impact on fuel consumption and the costs for shipping companies. The highly interdisciplinary AntifoMar project aims for the identification and total synthesis of natural products, isolated from sessile marine invertebrates, which have anti-fouling and anti-biofilm properties. My part in this project is the delopment of synthetic routes for this those compounds and potentialle improve their activity by making drug like analouges. 


  • Paulsen, Marianne Hagensen; Engqvist, Magnus; Ausbacher, Dominik; Anderssen, Trude; Langer, Manuel K-; Haug, Tor; Morello, Glenn Robert; Liikanen, Laura; Blencke, Hans-Matti; Isaksson, Johan; Juskewitz, Eric; Bayer, Annette; Strøm, Morten B.. Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates. Journal of Medicinal Chemistry 2021; Volum 64 (15). ISSN 0022-2623.s 11395 - 11417.s doi: 10.1021/acs.jmedchem.1c00734.
  • Rahman, Ataur; Langer, Manuel Karl; Dey, Hymonti; Hira, Jonathan; Mishchenko, Ekaterina; Bayer, Annette; Haug, Tor; Landfald, Bjarne; Sollid, Johanna U Ericson; Strøm, Morten B.; Stensvåg, Klara. Novel antimicrobial and biofilm-inhibitors from marine resources. Norwegian Biochemical Society Contact Meeting 2020 2020-01-23 - 2020-01-26 2020.
  • Look at all works in CRIStin →


    Research interests

    • Synthesis of tetra-substituted hydantions
    • selective alkylation of hydantoins
    • targeted substitution of barbituric acid

    Teaching

    Fall 2018: KJE-1001 - Introduction into chemistry and chemical biology

    • Supervision of laboratory exercises

     


    Member of research group



    Realfagbygget C418