Department of Chemistry +4777644084 94086741 Tromsø Realfagbygget C418

Manuel K Langer

Doctoral Research Fellow, Chemical Synthesis and Analysis

Job description

Fouling (growth of bacteria and bigger structures on solid surfaces) on marine vessels has a huge impact on fuel consumption and the costs for shipping companies. The highly interdisciplinary AntifoMar project aims for the identification and total synthesis of natural products, isolated from sessile marine invertebrates, which have anti-fouling and anti-biofilm properties. My part in this project is the delopment of synthetic routes for this those compounds and potentialle improve their activity by making drug like analouges. 

  • Paulsen, Marianne Hagensen; Engqvist, Magnus; Ausbacher, Dominik; Anderssen, Trude; Langer, Manuel K-; Haug, Tor; Morello, Glenn Robert; Liikanen, Laura; Blencke, Hans-Matti; Isaksson, Johan; Juskewitz, Eric; Bayer, Annette; Strøm, Morten B.. Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates. Journal of Medicinal Chemistry 2021; Volum 64 (15). ISSN 0022-2623.s 11395 - 11417.s doi: 10.1021/acs.jmedchem.1c00734.
  • von Hofsten, Susannah; Paulsen, Marianne Hagensen; Langer, Manuel K; Norvoll Magnussen, Synnøve; Ausbacher, Dominik; Bayer, Annette; Strøm, Morten B.; Berge, gerd. A Compound Inspired by Arctic Marine Animals Kills Cancer Cells in vitro and in vivo. IMB Conference 2022 2022-06-13 - 2022-06-14 2022.
  • Rahman, Ataur; Langer, Manuel Karl; Dey, Hymonti; Hira, Jonathan; Mishchenko, Ekaterina; Bayer, Annette; Haug, Tor; Landfald, Bjarne; Sollid, Johanna U Ericson; Strøm, Morten B.; Stensvåg, Klara. Novel antimicrobial and biofilm-inhibitors from marine resources. Norwegian Biochemical Society Contact Meeting 2020 2020-01-23 - 2020-01-26 2020.
  • Look at all works in CRIStin →

    Research interests

    • Synthesis of tetra-substituted hydantions
    • selective alkylation of hydantoins
    • targeted substitution of barbituric acid


    Fall 2018: KJE-1001 - Introduction into chemistry and chemical biology

    • Supervision of laboratory exercises


    Member of research group

    Realfagbygget C418