Jayalal K Jayanthan
Jayalal K Jayanthan is a PhD student in the Seafood Science research group at the Norwegian College of Fisheries Science, UiT Campus Tromsø. Jayalal's work is primarily focused on studying the gut microbiota and its impact on the onset and development of atherosclerosis. This exploration uses a mouse model fed with novel low-trophic marine resources. This research is one of a central parts of the SECURE project, which aims to renew sustainable marine resources for food security through a multidisciplinary approach.
For more details on Jayalal's research interests and teaching activities, see the following page.
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As I embark on my PhD, I am drawn to the complex dynamics of the cardiovascular system, with a particular focus on the origin and impact of atherosclerosis. This disease, which is primarily characterized by the build-up of plaque within the walls of arteries, leads to impaired blood flow and sets the stage for blood clots to form. The intriguing overlap of risk factors - unhealthy dietary practices, physical inactivity and obesity - increases the risk of cardiovascular disease, which often culminates in hypercholesterolemia. On a deeper level, my interest is sparked by the integral role played by the gut microbiota. This versatile conductor expertly balances our immune function, metabolism and barrier function under normal physiological conditions. However, this balance can be disrupted by external factors such as diet, infections and physical activity, potentially affecting our overall health. Existing research indicates a discernible alteration in the gut microbiome of individuals affected by atherosclerosis, often associated with dietary habits that promote hypercholesterolaemia.
My research focuses on the potential benefits of seafood consumption in reducing the risk of cardiovascular disease in humans. Previous studies have shown promising avenues, particularly highlighting the importance of low-trophic marine food resources. I am keen to further explore this area and investigate the effects of low-trophic seafood on the gut microbiome using animal models of atherosclerosis. In this investigative process, it is crucial to unravel the complex web of atherosclerosis progression and its relationship to the gut microbiome and microbial metabolism. My PhD thesis aims to answer these important questions using state-of-the-art molecular techniques, next-generation sequencing, bioinformatics, and data analysis tools.
In this ambitious endeavor, I am driven by a desire to demystify the intricate interplay of nutrition, gut microbiota and cardiovascular health. By bridging the knowledge gaps, I hope to make meaningful contributions to this important area of nutrition and health research.
- BIO-2018 Genetics, Molecular Biology and Bioinformatics
- FSK-2053 Data science and bioinformatics for fisheries and aquaculture
- BIO-3607 Food Safety
- FSK-2030 Sustainable Aquaculture
Member of research group
Member of project
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