Newly accepted papers
Publications 2023
M. Giambelluca*, E. Markova*, B. Steinkjer, R. Sundset, N. Škalko-Basnet and Sjoerd Hak (2023) Liposomes - human phagocytes interplay in whole blood: effect of liposome design. Nanomedicine: Nanotechnology, Biology, and Medicine, accepted (* shared first authorship)
A. Sousa, V. Borøy, A. Bæverud, K. Julin, A. Bayer, M. Strøm, M. Johannessen, N. Skalko-Basnet
and S. Obuobi (2023). Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa, Journal of Materials Chemistry B, acepted, DOI: 10.1039/d3tb00704a
Jakubec M, Rylandsholm F.G., Rainsford P., Silk M., Bril'kov M., Kristoffersen T., Juskewitz E., Ericson J.U. and Svendsen J.S.M. (2023). Goldilocks dilemma: LPS works both as the initial target and a barrier for the antimicrobial action of cationic AMPs on E. coli. Biomolecules. 2023 Jul 20;13(7):1155
Hemmingsen, L. M., Panzacchi, V., Mbugua Kangu, L., Giordani, B., Luppi, B. and N. Škalko-Basnet (2023)
Lecithin and chitosan as building blocks in anti-Candida clotrimazole nanoparticles. Pharmaceuticals, accepted in Special Issue Pharmaceutical Excipients in Formulation Design and Drug Delivery
Čačić, A., Amidžić Klarić, D., Keser, S., Radiković, M., Rukavina, Z., Jøraholmen, M.W., Uzelac, l., Kralj, M., Škalko-Basnet, N., Šegvić Klarić, M. and Vanić. Ž. (2023)
A novel approach for the treatment of aerobic vaginitis: azithromycin liposomes-in-chitosan hydrogel. Pharmaceutics,15, 1356. Special issue on “Advances in Vaginal Drug Delivery” https://doi.org/10.3390/pharmaceutics15051356
J.T. Lynnerup, J.B. Eriksen, A. Bauer-Brandl, A. M. Holsæter, M. Brandl. (2023)
Insight into the mechanism behind oral bioavailability-enhancement by nanosuspensions through combined dissolution/permeation studies. European Journal of Pharmaceutical Sciences, 184, 106417 (https://doi.org/10.1016/j.ejps.2023.106417)
Sousa, A., Ngoc Phung, A., Škalko-Basnet, N. and Obuobi, S. (2023)
Smart Delivery Systems for Microbial Biofilm Therapy: Carrier Design, Drug Release and Toxicology. Journal of Controlled Release, 354, 394-416 (DOI: https://doi.org/10.1016/j.jconrel.2023.01.003)
L. Myrseth Hemmingsen, B. Giordani, M. H. Paulsen, Ž. Vanić, G. Eide Flaten, B. Vitali, P. Basnet, A. Bayer, M. B. Strøm and N. Škalko-Basnet (2023)
Tailored anti-biofilm activity – liposomal delivery for mimic of small antimicrobial peptide. Biomaterials Advances, accepted (Journal is formerly known as Materials Science and Engineering: C; IF 8.4) (DOI: 10.1016/j.bioadv.2022.213238)
Publications 2022
L. M. Hemmingsen, P. Panchai, K. Julin, P. Basnet, M. Nystad, M. Johannessen and N. Skalko-Basnet (2022)
Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine. Frontiers in Microbiology, section Infectious Agents and Disease, accepted
A. M. Holsæter, K. Wizgird, I. Karlsen, J. F. Hemmingsen, M. Brandl, N. Skalko-Basnet (2022)
How docetaxel entrapment, vesicle size, zeta potential and stability change with liposome composition–A formulation screening study. European Journal of Pharmaceutical Sciences. https://doi.org/10.1016/j.ejps.2022.106267
N. Jayakumar, F. T. Dullo, V. Dubey, A. Ahmad, F. Ströhl, J. Cauzzo, E. Mazagao Guerreiro, O. Snir, N. Skalko-Basnet, K. Agarwal and B. Singh Ahluwalia (2022) Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy. Nanophotonics, https://doi.org/10.1515/nanoph-2022-0100
M.W. Jøraholmen, P. Damdimopoulou, G. Acharya and N. Škalko-Basnet (2022) Toxicity Assessment of Resveratrol Liposomes-in-hydrogel Delivery System by EpiVaginalTM Tissue Model, Pharmaceutics, 14, 1295. Special Issue Novel Vaginal Drug Delivery Systems. https://doi.org/10.3390/pharmaceutics14061295
E. A. L. Rustad, S. von Hofsten, R. Kumar, E. A. Lænsman, G. Berge and N. Skalko-Basnet (2022)
The pH-responsive liposomes –The effect of PEGylation on release kinetics and cellular uptake in glioblastoma cells. Pharmaceutics, A Commemorative Issue in Honor of Professor Gregory Gregoriadis: Liposomes for the Delivery of Drugs and Vaccines, accepted
P. Rainsford, R.B. Sarre, B.O. Brandsdal, M. Falavigna, G.E. Flaten, M. Jakubec and J. Isaksson (2022),
WIND-PVPA: Water/Ion NMR Detected PVPA to assess lipid barrier integrity in vitro through quantification of passive water- and ion transport, BBA – Biomembranes, accepted
S. Obuobi, A. Ngoc Phung, K. Julin, M. Johannessen, and N. Skalko-Basnet (2022) Biofilm Responsive Zwitterionic Antimicrobial Nanoparticles to Treat Cutaneous Infection. Biomacromolecules, 23, 303-315, pubs.acs.org/doi/10.1021/acs.biomac.1c01274
Publications 2021
L. M. Hemmingsen, N. Skalko-Basnet and M. W. Jøraholmen (2021) The Expanded Role of Chitosan in Localized Antimicrobial Therapy. Marine Drugs, Special Issue: Evaluation of Bioactive Properties of Marine-Derived Polysaccharides and Oligosaccharides, invited review, accepted
J. Grip, E. Steene, R. E. Engstad, J. Hart, A. Bell, I. Skjæveland, P. Basnet, N. Škalko-Basnet, and A. M. Holsæter(2018). Development of a novel beta-glucan supplemented hydrogel spray formulation and wound healing efficacy in a db/db diabetic mouse model, European Journal of Pharmaceutics and Biopharmaceutics,169, 280-291. DOI: https://doi.org/10.1016/j.ejpb.2021.10.013
V. Kalidasan, X. Yang, Z. Xiong, R.R. Li, H. Yao, H. Godaba, S. Obuobi, P.Singh, X. Guan, X. Tian, S. A. Kurt, Z. Li, D. Mukherjee, R. Rajarethinam, C. S. Chong, J.-W. Wang, P. L. Rachel Ee, W. Loke, B. C. K. Tee, J. Ouyang, C. J. Charles & J. S. Ho (2021) Wirelessly operated bioelectronic sutures for the monitoring of deep surgical wounds, Nature Biomedical Engineering 5,1217–1227
I. Laidmäe, A. Meos, I. A. Kjærvik, S. G. Ingebrigtsen, N. Škalko-Basnet, K. Kirsimäe, T. Romann, U. Joost, V. Kisand and K. Kogermann (2021) Electrospun Amphiphilic Nanofibers as Templates for In Situ Preparation of Chloramphenicol-Loaded Liposomes, Pharmaceutics, 13, 1742. https://doi.org/10.3390/pharmaceutics13111742
L. V. Schulte-Werning, A. Murugaiah, B. Singh, M. Johannessen, R. E. Engstad, N. Škalko-Basnet and A. M. Holsæter (2021) Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-inflammatory Properties prepared by Needle-free Electrospinning. Pharmaceutics, accepted
M. Šoltys, D. Zůza, T. Boleslavská, S. Akhlasová, M. Balouch, P. Kovačík, J. Beránek, N. Škalko-Basnet, G.E. Flaten and F. Štěpánek (2021) Drug loading to mesoporous silica carriers by solvent evaporation: A comparative study of amorphization capacity and release kinetics, International Journal of Pharmaceutics, 607, 120982
G.E. Flaten, Z. Vanic, N.Skalko-Basnet (2021)
The Role of In Vitro Skin Models in Optimization of Dermal Drug Delivery, in N.Dragićević and H. Maibach (eds), Percutaneous Absorption, Fifth edition, Taylor and Francis, 693-714
M. W. Jøraholmen, S. Ternullo, A. M. Holsæter, G.E. Flaten, and N. Škalko-Basnet (2021)
Advanced Drug Delivery Systems for Biologics, in H. A. E. Benson et al (eds) Fundamentals of Drug Delivery Fundamentals of Drug Delivery, First Edition, John Wiley & Sons, 231-259
Ž. Vanić, M. W. Jøraholmen and N. Škalko-Basnet (2021)
Nanomedicines for the topical treatment of vulvovaginal infections: addressing the challenges of antimicrobial resistance. Advanced Drug Delivery Reviews, accepted
L. M. Hemmingsen, K. Julin, L. Ahsan, P. Basnet, M. Johannessen and N. Škalko-Basnet (2021)
Chitosomes-in-chitosan hydrogel for acute skin injuries: prevention and infection control. Marine Drugs, 19, 269 ,Special Issue "Wound Healing Potential of Marine Natural Products", accepted
J. Cauzzo, N. Jayakumar, B. Singh Ahluwalia, A. Ahmad and N. Škalko-Basnet (2021) Characterization of Liposomes Using Quantitative Phase Microscopy (QPM). Pharmaceutics 13, 590, Special issue Advances in Characterization Methods for Drug Delivery Systems. https://doi.org/10.3390/pharmaceutics13050590
L. M. Hemmingsen, B. Giordani, A. K. Pettersen, B. Vitali, P. Basnet and N. Škalko-Basnet (2021)
Liposomes-in-chitosan hydrogel boosts potential of chlorhexidine in biofilm eradication in vitro. Carbohydrate Polymers, accepted
Z. Vinarov, B. Abrahamsson, P. Artursson, H. Batchelor, P. Berben, A. Bernkop-Schnürch, J. Butler, J. Ceulemans, N. Davies, D. Dupont, G.E. Flaten, N. Fotaki, B. Griffin, V. Jannin, J. Keemnik, F. Kesisolgou, M. Koziolek, M. Kuentz, A. Mackie, U. Maran, A. J. M. Martinez, M. McAllister, A. Müllertz, C. O’Driscoll, N.Parrott, J. Paszkowska, P. Pavek, C. Porter, C. Reppas, C. Stillhart, K. Sugano, E.Toader, K. Valentová, M. Vertzoni, S. De Wildt, C. G. Wilson, P. Augustijns (2021) Current challenges and future perspectives in oral absorption research: an opinion of the UNGAP network, Advanced Drug Delivery Reviews, 117, 289-331
M. Falavigna, S. Brurok, M. Klitgaard, G.E. Flaten (2021)
Simultaneous assessment of in vitro lipolysis and permeation in the mucus-PVPA model to predict oral absorption of a poorly water soluble drug in SNEDDSs, Int J Pharm, 596,12025, DOI:https://doi.org/10.1016/j.ijpharm.2021.120258
M. Falavigna, M. Klitgaard, R. Berthelsen, A. Müllertz, G.E. Flaten (2021)
Predicting oral absorption of fenofibrate in lipid-based drug delivery systems by combining in vitro lipolysis with the mucus-PVPA permeability model, JPharmSci, 110, 208-216, DOI:https://doi.org/10.1016/j.xphs.2020.08.026
Publications 2020
V. Selvarajan, S.A.O. Obuobi, R.E. Pui Lai (2020). Silica Nanoparticles—A Versatile Tool for the Treatment of Bacterial Infections. Frontiers in Chemistry 2020, 8 (602), DOI: 10.3389/fchem.2020.00602
M. W. Jøraholmen, M. Johannessen, K.Gravningen, M. Puolakkainen, G. Acharya, P. Basnet and N. Škalko-Basnet (2020) Liposomes-in-hydrogel delivery system enhances the potential of resveratrol in combating vaginal chlamydia infection. Pharmaceutics, Special Issue on Local Antibacterial and Antimicrobial Drug Delivery Systems, 12, 1203; doi:10.3390/pharmaceutics12121203
Obuobi S., Mayandi V, Nurul A, Lee B, Lakshminarayanan R, Ee PLR. (2020)
Nucleic acid peptide nanogels for the treatment of bacterial keratitis, NANOSCALE doi: 10.1039/d0nr03095c
J. Cauzzo, M. Nystad, A .M. Holsæter, P. Basnet and N. Škalko-Basnet (2020)
Following the fate of dye-containing liposomes in vitro. International Journal of Molecular Sciences, accepted
Sybil Obuobi and Nataša Škalko-Basnet (2020)
Nucleic Acid Hybrids as Advanced Antibacterial Nanocarriers. Pharmaceutics, special issue Hybrid Multifunctional Drug Delivery Systems, accepted
M. Falavigna, M. Pattacini, R. Wibel, F. Sonvico, N.Škalko-Basnet, G.E. Flaten (2020)
The vaginal-PVPA: a vaginal mucosa-mimicking in vitro permeation tool for evaluation of mucoadhesive formulations, Pharmaceutics, 12, 568
S. Obuobi, K.Julin, E. G. Fredheim, M. Johannessen and N. Škalko-Basnet (2020)
Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced drug loading and synergistic anti-inflammatory activity against S. aureus intracellular infections, Journal of Controlled Release, 324, 620-632
Jian Yao Ng, Sybil Obuobi, Mei Ling Chua, Chi Zhang, Shiqi Hong, Yogesh Kumar, Rajeev Gokhale and Pui Lai Rachel Ee (2020) Biomimicry of microbial polysaccharide hydrogels for tissue engineering and regenerative medicine – A review. Carbohydrate Polymers 241, 116345.
M. Falavigna, P.C. Stein, G. E. Flaten and M. P. di Cagno (2020)
Impact of Mucin on Drug Diffusion: Development of a Straightforward in Vitro Method for the determination of Drug Diffusivity in the Presence of Mucin" Pharmaceutics, 12, 168, Special Issue Mucoadhesive and Mucosal Drug Delivery Systems, doi:10.3390/pharmaceutics12020168
M.W. Jøraholmen, A. Bhargava, K. Julin, M. Johannessen and N. Škalko-Basnet (2020)
The Antimicrobial Properties of Chitosan Can be Tailored by Formulation. Marine Drugs 18, 96. Special Issue Marine Chitin 2019, doi:10.3390/md18020096
F. Alopaeus, M. Hellfritzsch, T. Gutowski, R. Scherließ, A. Almeida, B. Sarmento, N. Škalko-Basnet and Ingunn Tho (2020) Mucoadhesive buccal films based on a graft co-polymer – A mucin-retentive hydrogel scaffold. Eur. J. Pharm. Sci., 142, 105142, DOI: 10.1016/j.ejps.2019.105142
B. Giordani, P. Basnet, E. Mishchenko, B. Luppi and N. Škalko-Basnet (2020)
Utilizing liposomal quercetin and gallic acid in localized treatment of vaginal Candida infections. Pharmaceutics, 12, 9
Ternullo, L. V. Schulte Werning, A. M. Holsæter and N. Škalko-Basnet (2020)
Curcumin-in-deformable liposomes-in-chitosan-hydrogel as novel wound dressing. Pharmaceutics,12, 8, Special issue Semisolid Dosage Forms
Publications 2019
S. Ternullo, E. Gagnat, K. Julin, M. Johannessen, P. Basnet, Ž. Vanić, N. Škalko-Basnet (2019)
Liposomes augment biological benefits of curcumin for multitargeted skin therapy. European Journal of Pharmaceutics and Biopharmaceutics, 144, 154-164, https://doi.org/10.1016/j.ejpb.2019.09.016
Wu, I. Y., Bala, S., Škalko-Basnet, N. & Di Cagno, M. P. (2019)
Interpreting non-linear drug diffusion data: Utilizing Korsmeyer-Peppas model to study drug release from liposomes. Eur J Pharm Sci, 138, 105126
Ž. Vanić, Z. Rukavina, S. Manner, A. Fallarero, L. Uzelac, M. Kralj, D. Amidžić Klarić, A. Bogdanov, T. Raffai, D. P. Virok, J. Filipović-Grčić, N. Škalko-Basnet (2019)
Azithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections. International Journal of Nanomedicine, 14, 5957-5976
J. H. Hansen and R. Fjellaksel (2019)
Catalytic Intermolecular Functionalization of Benzimidazoles, IntechOpen, DOI: 10.5772/intechopen.87068. (book chapter)
M.P di Cagno, P. C. Stein (2019)
Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy, European Journal of Pharmaceutics and Biopharmaceutics, accepted
I.Y. Wu, T.E. Nikolaisen, N. Škalko-Basnet and M.P. di Cagno (2019)
The hypotonic environmental changes affect liposomal formulations for nose-to-brain targeted drug delivery, Journal of Pharmaceutical Sciences, 108(8), 2570-2579. DOI: 10.1016/j.xphs.2019.03.006.
M. Falavigna, M. Klitgaard, E. Steene and G.E. Flaten (2019)
Mimicking regional and fasted/fed state conditions in the intestine with the mucus-PVPA in vitro model: the impact of pH and simulated intestinal fluids on drug permeability, European Journal of Pharmaceutical Sciences, 132, 44-54. https://doi.org/10.1016/j.ejps.2019.02.035
M.W. Jøraholmen, P. Basnet, M.J. Tostrup, S. Moueffaq, N. Skalko-Basnet (2019)
Localized therapy of vaginal infections and inflammation: Liposomes-in-hydrogel delivery system for polyphenols, Pharmaceutics (open access journal IF 3.746; SPECIAL ISSUE: Feature Papers for 10th Anniversary of Pharmaceutics ), 11, 53; doi:10.3390/pharmaceutics11020053
Publications 2018
R.Fjellaksel, A. Oteiza, M. Martin-Armas, P. J. Riss, O. K. Hjelstuen, S.l Kuttner, J. H. Hansen, R. Sundset (2018) First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor, BMC Research Notes, doi.org/10.1186/s13104-018-3924-2
S. Ternullo, P. Basnet, A. M. Holsæter, G. E. Flaten, L. de Weerd, N. Škalko-Basnet (2018)
Deformable liposomes for skin therapy with human epidermal growth factor: The effect of liposomal surface charge. European Journal of Pharmaceutical Sciences, in press, doi:10.1016/j.ejps.2018.10.005
J. Grip , R. E. Engstad, I. Skjæveland, N. Škalko-Basnet, J. Isaksson, P. Basnet and A. M. Holsæter (2018)
Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice, European Journal of Pharmaceutical Sciences, accepted
T. Wagner, B. Joshi B, J. Janice, F. Askarian, N. Škalko-Basnet, O. C. Hagestad, A. Mekhlif, S. N. Wai, K. Hegstad and M. Johannessen (2018) Enterococcus faecium produces membrane vesicles containing virulence factors and antimicrobial resistance related proteins, Journal of Proteomics, accepted
P. Berben, A. Bauer-Brandl, M. Brandl, B. Faller, G. E. Flaten, A.. Jacobsen, J. Brouwers and P. Augustijns (2018)
Drug Permeability Profiling using Cell-Free Permeation Tools: An Overview and Their Applications, Eur J Pharm Sci, 119, p 219-233
R. Fjellaksel, R. Sundset, J.H. Hansen and P.J. Riss (2018)
Copper-mediated late-stage iodination and 123I-labelling of triazole-benzimidazole bioactives. Synlett, DOI: 10.1055/s-0036-1591985
M.P. di Cagno, F. Clarelli, J. Våbenø, C. Lesley, S.D. Rahman, J. Cauzzo, E. Franceschinis, N. Realdon, and P.C. Stein (2018), Experimental determination of drug diffusion coefficients in unstirred aqueous environments by temporally resolved concentration measurements, Mol. Pharmaceutics, DOI:10.1021/acs.molpharmaceut.7b01053
R. Fjellaksel, D. Dugalic, T.B. Demissie, P.J. Riss, O.K. Hjelstuen, R. Sundset and J.H. Hansen (2018)
An Acylation-Finkelstein Approach to Radioiodination of Bioactives: The Role of Amide Group Anchimeric Assistance. Journal of Physical Organic Chemistry, DOI
M. Falavigna, M. Klitgaard, C. Brase, S. Ternullo, N. Škalko-Basnet, G. E. Flaten (2018)
Mucus-PVPA (Mucus Phospholipid Vesicle-based Permeation Assay): an artificial permeability tool for drug screening and formulation development, Int J Pharm, 537, 213–222, DOI: 10.1016/j.ijpharm.2017.12.038
Publications 2017
Ž. Vanić and N. Škalko-Basnet (2017)
Nanoformulations for Vaginal Therapy, in Rai, M. and dos Santos C. A. (Eds) Nanotechnology Applied to Pharmaceutical Technology, Springer International Publishing AG, Cham, Switzerland, pp. 183-221. ISBN 978-3-319-70298-8 ISBN 978-3-319-70299-5 (eBook)
R.Fjellaksel, M. Boomgaren, R. Sundset, I. H. Haraldsen, J.H. Hansen and P. J. Riss (2017)
Small molecule piperazinyl-benzimidazole antagonists of the gonadotropinreleasing hormone (GnRH) receptor, Med. Chem. Commun., 8, 1965-1969, DOI: 10.1039/C7MD00320J.
S. Ternullo, L. de Weerd, A. M. Holsæter, G. E. Flaten, N. Škalko-Basnet (2017)
Going skin deep: a direct comparison of penetration potential of lipid-based nanovesicles on the isolated perfused human skin flap model, European Journal of Pharmaceutics and Biopharmaceutics, 121, 14-23
Ž. Vanić and N. Škalko-Basnet (2017)
Hydrogels for Vaginal Drug Delivery, in Functional hydrogels in drug delivery: key features and future perspectives, (Eds) U. G. Spizzirri, G. Cirillo, CRC Press/ Taylor & Francis Group, Boca Raton, USA, pp. 259-300. ISBN 9781498749015
J. Grip, R. E. Engstad, I. Skjæveland, N. Skalko-Basnet, A.M. Holsæter (2017)
Sprayable Carbopol hydrogel with soluble beta-1,3/1,6-glucan as an active ingredient for wound healing – development and in-vivo evaluation. European Journal of Pharmaceutical Sciences, 107, 24-31
A. Øverbye, A. M. Holsæter, M. Fusser, N. Škalko-Basnet, T-G. Iversen, M. Lyngaas Torgersen, T. Sønstevold, O. Engebraaten, K. Flatmark, G.M. Mælandsmo, T. Skotland, K. Sandvig (2017) Ceramide-containing liposomes with doxorubicin: Time and cell-dependent effect of C6 and C12 ceramide, Oncotarget, 8(44), 76921-76924
J. Kumari, G. Eide Flaten, N. Škalko-Basnet and H. Tveiten (2017)
Molecular transfer to Atlantic salmon ovulated eggs using liposomes, Aquaculture, 479, 404–411, doi:10.1016/j.aquaculture.2017.06.019
I. Y. Wu, N. Škalko-Basnet, M. P. di Cagno (2017) Influence of the environmental tonicity perturbations on the release of model compounds from large unilamellar vesicles (LUVs): a mechanistic investigation, Colloids and Surfaces B: Biointerfaces, 157, 65–71
S.G. Ingebrigtsen, A. Didriksen, M. Johannessen, N. Škalko-Basnet and A. M. Holsæter (2017)
Old drug, new wrapping – A possible comeback for chloramphenicol? International Journal of Pharmaceutics, 526, 538- 546, DOI: 10.1016/j.ijpharm.2017.05.025
M. Falavigna, N. Škalko-Basnet, C. Cavallari, Andrea Pini, B. Luppi and M. P. di Cagno (2017)
Novel in situ gel-forming solid dosage form (gfSDF) prepared by simple syringe-based moulding: a screening study, European Journal of Pharmaceutical Sciences, 105, 11-12, http://dx.doi.org/10.1016/j.ejps.2017.05.008
U Massing, S. G. Ingebrigtsen, N. Skalko-Basnet and A. M. Holsæter (2017)
Dual Centrifugation - A Novel "In Vial" Liposome Processing Technique, Liposomes, InTech, ISBN 978-953-51-5467-9
T. Andersen, E. Mishchenko, G. E. Flaten, J. Sollid, S. Mattsson, I. Tho and N. Skalko-Basnet (2017)
Chitosan-based nanomedicine to fight genital Candida infections: Chitosomes, Marine Drugs, 15, 64, doi:10.3390/md15030064
N. Škalko-Basnet and Ž. Vanić (2017)
Lipid-based Nanopharmaceuticals in Antimicrobial Therapy, in Functionalized Nanomaterials for the Management of Microbial Infection, A Strategy to Address Microbial Drug Resistance, 1st Edition, (Eds) R. Boukherroub, S. Szunerits, D. Drider, Elsevier, Amsterdam, The Netherlands, pp. 111-151. ISBN: 9780323416252
M. P. Di Cagno (2017),
The potential of cyclodextrins as novel active pharmaceutical ingredients, Molecules, 22, 1
M. W. Jøraholmen, P. Basnet, G. Acharya and N. Škalko-Basnet (2017)
PEGylated liposomes for topical vaginal therapy improve delivery of interferon alpha. European Journal of Pharmaceutics and Biopharmaceutics, 113, 132-139
S. G. Ingebrigtsen, N. Škalko-Basnet, C. de A. C. Jacobsen and A. M. Holsæter (2017)
Successful co-encapsulation of benzoyl peroxide and chloramphenicol in liposomes by a novel manufacturing method - dual asymmetric centrifugation, European Journal of Pharmaceutical Sciences, 97, 192-199, http://dx.doi.org/10.1016/j.ejps.2016.11.017
S. Ternullo, L. de Weerd, G. E. Flaten, A. M. Holsæter and N. Škalko-Basnet (2017)
The isolated perfused human skin flap model: A missing link in skin penetration studies? European Journal of Pharmaceutical Sciences, 96(1), 334-341, http://dx.doi.org/10.1016/j.ejps.2016.10.003
Publications 2016
A. Konstantinell, J.-A. Bruun, R. Olsen, A. Aspar, N. Škalko-Basnet, B. Sveinbjørnsson and U. Moens (2016) Secretomic Analysis of Extracellular Vesicles Originating from Polyomavirus-Negative and Polyomavirus-Positive Merkel Cell Carcinoma Cell Lines, Proteomics, 16, 2587-91, http://dx.doi.org/10.1002/pmic.201600223
E. Hagen, F.S. Løding, S. Mattsson, I. Tho (2016)
Use of interactive mixtures to obtain mini-tablets with high dose homogeneity for paediatric drug delivery, Journal of Drug Delivery Science and Technology, 34, 51-59
A. Engesland, N. Škalko-Basnet, G. E. Flaten (2016)
In vitro models to estimate drug penetration through the compromised stratum corneum barrier, Drug Development and Industrial Pharmacy 42 (11), 1742-1751
V.Staven, S. Wang, I. Grønlie and I. Tho (2016)
Development and Evaluation of a Test Program for Y-site Compatibility Testing of Total Parenteral Nutrition and Intravenous Drugs, Nutrition Journal, early online, http://dx.doi.org/10.1186/s12937-016-0149-x
V. Staven, H. Iqbal, S. Wang, I. Grønlie and I. Tho (2016)
Physical compatibility of total parenteral nutrition and drugs in Y-site administration to children from neonates to adolescents. Journal of Pharmacy and Pharmacology, early online
S. G. Ingebrigtsen, N. Škalko-Basnet and A. M. Holsæter (2016)
Development and optimization of a new processing approach for manufacturing topical liposomes in-hydrogel drug formulations by dual asymmetric centrifugation, Drug Development and Industrial Pharmacy, 42 (9), 1375-83, http://dx.doi.org/10.3109/03639045.2015.1135940
I. Tamm, J. Heinämäki, I. Laidmäe, L. Rammo, U. Paaver, S. G. Ingebrigtsen, N. Škalko-Basnet, A. Halenius, J. Yliruusi, P. Pitkänen, Sami Alakurtti and Karin Kogermann (2016)
Development of suberin fatty acids and chloramphenicol loaded antimicrobial electrospun nanofibrous mats intended for wound therapy, Journal of Pharmaceutical Sciences, 105(3), 1239-47, http://dx.doi.org/10.1016/j.xphs.2015.12.025
Publications 2015
I. Tho and N. Škalko-Basnet (2015)
Cell-based in vitro models for vaginal permeability studies in Concepts and Models for Drug Permeability Studies: Cell and Tissue Based In Vitro Culture Models, Editor Bruno Sarmento, Elsevier, Amsterdam, book chapter
D. Stelzl, T. Terndrup Nielsen, T. Hansen, M. di Cagno (2015)
Beta-CD-dextran polymer for efficient sequestration of cholesterol from phospholipid bilayers: mechanistic and safe-toxicity investigations, International Journal of Pharmaceutics, accepted (IF:3.65)
M. W. Jøraholmen, N. Škalko-Basnet, G. Acharya, P. Basnet (2015)
Resveratrol-loaded liposomes for topical treatment of the vaginal inflammation and infections, European Journal of Pharmaceutical Sciences, 79, 112-121 (IF 3.35)
Hanady Bibi, Massimiliano di Cagno, Rene Holm, Annette Bauer-Brandl (2015)
PermeapadTM for investigation of passive drug permeability: the effect of surfactants, co-solvents and simulated intestinal fluids (FaSSIF and FeSSIF), International Journal of Pharmaceutics, 493, 192-197 (IF:3.65)
I. Colzi, A. N. Troyan, B. Perito, E. Casalone, R. Romoli, G. Pieraccini, N. Škalko-Basnet, A. Adessi, F. Rossi, C. Gonnelli, S. Ristori (2015) Antibiotic delivery by liposomes from prokaryotic microorganisms: similia cum similis works better. European Journal of Pharmaceutics and Biopharmaceutics, 94, 411-418 (IF 4.245)
Ž. Vanić, A.-M. Holsæter and N. Škalko-Basnet (2015)
(Phospho)lipid-based Nanosystems for Skin Administration, Current Pharmaceutical Design, special issue on "Nanotechnology for Drug Delivery", 21, 4174-4192 invited review (IF:3.29)
E. Naderkhani, T. Vasskog, G.E. Flaten (2015)
Biomimetic PVPA in vitro model for estimation of the intestinal drug permeability using fasted and fed state simulated intestinal fluids, European Journal of Pharmaceutical Sciences, 73, 64-71 (IF:3.35)
M. di Cagno, H. A. Bibi, A. Bauer-Brandl (2015)
New Biomimetic Barrier PermeapadTM for Efficient Investigation of Passive Permeability of Drugs, European Journal of Pharmaceutical Sciences, 73, 29–34 (IF:3.35)
M.W. Jøraholmen, G. Acharya and N. Škalko-Basnet (2015)
Kan nanopartikulære formuleringer bedre behandlingen av genitale infeksjoner? Norsk Farmaceutisk Tidsskrift, 4, 22-25
G.E Flaten, Z. Palac, A.Engesland, J. Filipović-Grčić, Ž. Vanić and N. Škalko-Basnet, (2015)
In vitro skin models as a tool in optimization of drug formulation, European Journal of Pharmaceutical Sciences, 75,10–24 (IF:3.35)
Z. Palac, J. Hurler, N. Škalko-Basnet, J. Filipović-Grčić, Ž. Vanić
Elastic liposomes-in-vehicle formulations destined for skin therapy: The synergy between type of liposomes and vehicle, Drug Development and Industrial Pharmacy, 41, 1247-1253 (IF:2.1)
Staven, V., Waaseth, M., Wang, S., Grønlie, I., Tho, I. (2015)
Utilization of the Tyndall effect for enhanced visual detection of particles in compatibility testing of intravenous fluids: Validity and reliability. PDA journal of pharmaceutical science and technology, 69, 270-283
T. Cerchiara, A. Abruzzo, M. di Cagno, F. Bigucci, A.Bauer-Brandl, C. Parolin, B. Vitali, B. Luppi (2015).
Micro and nanoparticulate chitosan-based systems for colon-targeted delivery of vancomycin: effect of drying methods. Eur.J. Pharm. Biopharm., 92, 112–119 (IF: 4.25)
A. Engesland, N. Škalko-Basnet, G. E. Flaten (2015)
PVPA and EpiSkin® in Assessment of Drug Therapies Destined for Skin Administration, Journal of Pharmaceutical Sciences, 104, 1119–1127 (IF: 3.01)
T. Andersen, S. Bleher, G.E. Flaten, I. Tho, S. Mattsson, N. Skalko-Basnet (2015)
Chitosan in mucoadhesive drug delivery: Local vaginal therapy, Marine Drugs, 13, 222-236 (IF: 3.5)
Publications 2014
Ž. Vanić and N. Škalko-Basnet (2014)
Mucosal nanosystems for improved topical drug delivery: Vaginal route of administration, Journal of Drug Delivery Science and Technology, 24, 435-444, invited review, (IF: 1.09)
Ž. Vanić, O. Planinšek, N. Škalko-Basnet and I. Tho (2014)
Tablets of pre-liposomes govern in situ formation of liposomes: Concept and potential of the novel drug delivery system, European Journal of Pharmaceutics and Biopharmaceutics, 88, 443-454 (IF: 3.83)
M. Hiorth, S. Nilsen, I. Tho (2014)
Bioadhesive Mini-Tablets for Vaginal Drug Delivery. Pharmaceutics, 6 (3) 494-511
M. W. Jøraholmen, Ž. Vanić, I. Tho and N. Škalko-Basnet (2014)
Chitosan-coated liposomes for topical vaginal therapy: Assuring localized drug effect, International Journal of Pharmaceutics, 472, 94-101 (IF:3. 46)
S.Fulsundar, K. Harms, G.E. Flaten, P. Johnsen, B. Chopade, and K. Nielsen (2014)
Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation, Applied and Environmental Microbiology, 80(11), 3469–3483 (IF:3.68)
E. Naderkhani , J. Isaksson, A. Ryzhakov, G.E. Flaten (2014)
Development of a biomimetic phospholipid vesicle-based permeation assay (PVPA) for the estimation of intestinal drug permeability, Journal of Pharmaceutical Sciences,103:1882–1890(IF: 3.13)
N. Škalko-Basnet (2014)
Biologics: the role of delivery systems in improved therapy, Biologics: Targets and Therapy, invited review, , 8, 107-114
Z. Palac, A. Engesland, G.E. Flaten, N. Škalko-Basnet, J. Filipović-Grčić, Ž. Vanić (2014)
Liposomes for (trans)dermal drug delivery: the skin-PVPA as a novel in vitro stratum corneum model in formulation development, Journal of Liposome Research, 24(4): 313–322 (IF: 1.91)
K. Berginc, S. Suljaković, N. Škalko-Basnet and A. Kristl (2014)
Mucoadhesive liposomes as new formulation for vaginal delivery of curcumin. European Journal of Pharmaceutics and Biopharmaceutics, 87, 40–46. (IF: 3.83)
E. Naderkhani, A. Erber, N. Škalko-Basnet, G.E. Flaten (2014)
Improved permeability of acyclovir: Optimization of mucoadhesive liposomes using the PVPA model, Journal of Pharmaceutical Sciences, 103, 661–668 (IF: 3.13)
Z. Vanić, J. Hurler, K. Ferderber, P. Golja Gašparović, N. Skalko-Basnet, J. Filipović-Grčić (2014)
Novel vaginal drug delivery system: Deformable propylene glycol liposomes-in-hydrogel, Journal of Liposome Research, 24(1): 27–36 (IF: 1.91)
Publications 2013
B. Thapa, I. Pepić, Ž. Vanić, P. Basnet and N. Škalko-Basnet (2013)
Topical delivery system for phytochemicals: Capsaicin and Capsicum tincture, Journal of Pharmaceutics and Drug Development, 1 (2), accepted
J. Hurler, K. K. Sørensen, A. Fallarero, P. Vuorela and N. Škalko-Basnet (2013)
Liposomes-in-hydrogel delivery system with mupirocin: in vitro anti-biofilm studies and in vivo evaluation in mice burn model. BioMed Research International, Pharmaceutics, Volume 2013, Article ID 498485, 8 pages
Whitaker, RD.; Ingebrigsten, SG; Naderkhani, E; Skar, M L; Flaten, GE (2013)
Investigation of parameters influencing incorporation, retention and cellular cytotoxicity in liposomal formulations of poorly soluble camptothecin, Journal of Liposome Research 23(4): 298-310
T. Andersen, Ž. Vanić, G. Eide Flaten, S. Mattsson, I. Tho, N. Škalko-Basnet (2013)
Pectosomes and chitosomes as delivery systems for metronidazole: The one-pot preparation method, Pharmaceutics, special issue on Liposome Technology, 5: 445-456
J. Hurler, S. Žakelj, J. Mravljak, S. Pajk, A. Kristl, R. Schubert, N. Skalko-Basnet (2013)
The effect of lipid composition and liposome size on the release properties of liposomes-in-hydrogel, International Journal of Pharmaceutics, 456: 49-57
Holsæter, A-M; Basnet, P and Škalko-Basnet, N (2013)
Fra droger til moderne legemidler; hvor viktig er formuleringen? Norsk Farmaceutisk Tidsskrift ,(7-8): 26-29
Engesland, A.; Skar, M.; Hansen, T.; Skalko-Basnet, N.; Flaten, G. E. (2013)
New Applications of PVPA: Permeation Model Mimicking Skin Barrier, Journal of Pharmaceutical Sciences, 102:1588-1600
Flaten, G.E.; Chang, T.T.; Phillips, W; Brandl, M.; Bao, A. and Goins, B (2013)
Liposomal Formulations of Poorly Soluble Camptothecin -Drug Retention and Biodistribution, Journal of Liposome Research, 23(1), 70-81
Ž. Vanić, N. Skalko-Basnet (2013) Nanopharmaceuticals for improved topical vaginal delivery: Can they deliver? European Journal of Pharmaceutical Sciences 50, 29-41.
Vanić, M. Bego, A. Hafner and N. Skalko-Basnet (2013),
The characterization of various deformable liposomes with metronidazole, Drug Development and Industrial Pharmacy, 39, 481-488
Hiorth, M.; Liereng, L.; Reinhartsen, R. and Tho,I. (2013)
Formulation of bioadhesive Hexylaminolevulinate pellets intended for photodynamic therapy in the treatment of cervical cancer, Int.J.Pharm., 441, 544–554
P. Basnet and N. Škalko-Basnet (2013)
Nanodelivery systems for improved topical antimicrobial therapy. Current Pharmaceutical Design 19, 7237-7243.
Basnet, Purusotam; Skalko-Basnet, Natasa; Hentemann, Martha Agnes; Acharya, Ganesh.
Development of polyphenols-containing nanoparticles for the treatment of vaginal inflammation. Pregnancy Hypertension 2013 ;Volum 3.(2) s. 92-93