Our projects

 

WP1 Biomarkers and systems biology

Plasma isolated from blood is easily accessible and therefore an attractive source for measuring potential biomarkers. Despite several previous targeted efforts, no predictive biomarker has been identified for incident VTE.

WP2 Functional studies

Identification of biomarkers and potential underlying molecular pathways of VTE in WP1 provides an excellent platform for further discovery of novel disease mechanisms

WP3 Prediction of VTE in arterial cardiovascular diseases

In the initial four-year period, we extensively investigated the bidirectional relationship between arterial and venous thrombosis. The next step will be to identify risk factors and triggers of VTE in these patient groups, and build prediction models that can stratify MI and stroke patients into high and low risk of VTE in order to guide clinical decisions on targeted prevention.