Publications

Selected publications (2010- up to date); h index (Google Scholar) 25

Villatoro A, Konieczny J, Cuminetti V, Arranz L. Leukemia stem cell release from the stem cell niche to treat acute myeloid leukemia. Front Cell Dev Biol 2020, 8: 607. doi: 10.3389/fcell.2020.00607

Cuminetti V, Arranz L. Bone Marrow Adipocytes: The Enigmatic Components of the Hematopoietic Stem Cell Niche. J Clin Med 2019, 8:707. doi: 10.3390/jcm8050707

Konieczny J, Arranz L. Updates on old and weary haematopoiesis. Int J Mol Sci 2018, 19:2567. doi: 10.3390/ijms19092567

Grimolizzi F, Arranz L. Multiple faces of succinate beyond metabolism in blood. Haematologica 2018, 103:1586–1592. doi: 10.3324/haematol.2018.196097

Bernal A, Arranz L. Nestin-expressing progenitor cells: function, identity and therapeutic implications. Cell Mol Life Sci 2018, 75:2177–2195. doi: 10.1007/s00018-018-2794-z 

*Arranz L, Arriero MM, Villatoro A. Interleukin-1β as emerging therapeutic target in hematological malignancies and potentially in their complications. Blood Rev 2017, 31:306-317.  doi: 10.1016/j.blre.2017.05.001. *Corresponding author

Sánchez-Aguilera A, Arranz L, Martín-Pérez D, García-García A, Stavropoulou V, Kubovcakova L, Isern J, Martín-Salamanca S, Langa X, Skoda RC, Schwaller J, Méndez-Ferrer S. Estrogen Signaling Selectively Induces Apoptosis of Hematopoietic Progenitors and Myeloid Neoplasms without Harming Steady-State Hematopoiesis. Cell Stem Cell 2014, 15:791-804.

Isern J, García-García A, Martín AM, Arranz L, Martín-Pérez D, Torroja C, Sánchez-Cabo F, Méndez-Ferrer S. The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem-cell-niche function. eLife 2014, 10.7554/eLife.03696.

Arranz L, Sánchez-Aguilera A, Martín-Pérez D, Isern J, Langa X, Tzankov A, Lundberg P, Muntión S, Tzeng Y-S, Lai D-M, Schwaller J, Skoda RC, Méndez-Ferrer S. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature 2014, 512:78-81.

Arranz L, Urbano-Ispizúa A, Méndez-Ferrer S. Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells. Haematologica 2013, 98:993-995.

Isern J, Martín-Antonio B, Ghazanfari R, Martín AM, del Toro R, Sánchez-Aguilera A, Arranz L, Martín-Pérez D, López JA, Suárez-Lledó M, Marín P, Van Pel M, Vázquez J, Fibbe WE, Scheding S, Urbano-Ispizúa A, Méndez-Ferrer S. Self-renewing human mesenspheres promote hematopoietic stem cell expansion. Cell Rep 2013, 3:1714-1724.

Arranz L, Méndez-Ferrer S. Network anatomy and in vivo physiology of mesenchymal stem cells. Inflamm Regen 2013, 33:38-47.

Arranz L, Naudí A, De la Fuente M, Pamplona R. Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage. Age (Dordr) 2013, 35:621-635.

Arranz L, De Castro NM, Baeza I, Giménez-Llort L, De la Fuente M. Effect of environmental enrichment on the immunoendocrine aging of male and female triple-transgenic 3xTg-AD mice for Alzheimer's disease. J Alzheimers Dis 2011, 25:727-737.

Arranz L, De Castro NM, Baeza I, Maté I, Viveros MP, De la Fuente M. Environmental enrichment improves age-related immune system impairment: long-term exposure since adulthood increases life span in mice. Rejuvenation Res 2010, 13:415-428. Erratum in: Rejuvenation Res 2010, 13:627.

Arranz L, Caamaño J, Lord JM, De la Fuente M. Preserved immune functions and controlled leucocyte oxidative stress in long-lived mice: possible role of nuclear factor-kappaB. J Gerontol A Biol Sci Med Sci 2010, 65:941-950.

Arranz L, Lord JM, De la Fuente M. Preserved ex vivo inflammatory status and cytokine responses in naturally long-lived mice. Age (Dordr) 2010, 32:451-466.

Arranz L, De Castro NM, Baeza I, De la Fuente M. Differential expression of Toll-like receptor 2 and 4 on peritoneal leukocyte populations from long-lived and non-selected old female mice. Biogerontology 2010, 11:475-482.

 

Book chapters

De la Fuente M, Arranz L. The importance of the environment in brain aging: Be happy, live longer! Brain Aging and Therapeutic Interventions 2013, pp: 79-94. doi: 10.1007/978-94-007-5237-5_6