Publications

Selected publications (2010- up to date); h index (Google Scholar) 26

#Villatoro A, #Cuminetti V, Bernal A, Torroja C, Cossío I, Benguría A, Ferré M, Konieczny J, Vázquez E, Rubio A, Utnes P, You X, Fenton CG, Paulssen RH, Zhang J, Sánchez-Cabo F, Dopazo A, Vik A, Anderssen E, Hidalgo A, Arranz LEndogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation. Nat Commun 2023, 14: 12. doi: 10.1038/s41467-022-35700-9. #Equal contribution.

Vilaplana-Lopera N, #Cuminetti V, #Almaghrabi R, #Papatzikas G, Rout AK, Jeeves M, González E, Alyahyawi Y, Cunningham A, Erdem A, Schnütgen F, Raghavan M, Potluri S, Cazier J-B, Schuringa JJ, Reed MAC, Arranz L, *Günther UL, *Garcia P. Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells. eLife 2022, 11: e75908. doi: 10.7554/eLife.75908. #Equal contribution; *Corresponding authors

Arranz L. The Hematology of Tomorrow is Here - Preclinical models Are Not: Cell Therapy for Hematological Malignancies. Cancers 2022, 14: 580. doi: 10.3390/cancers14030580

Villatoro A, Konieczny J, Cuminetti V, Arranz L. Leukemia stem cell release from the stem cell niche to treat acute myeloid leukemia. Front Cell Dev Biol 2020, 8: 607. doi: 10.3389/fcell.2020.00607

Cuminetti V, Arranz L. Bone Marrow Adipocytes: The Enigmatic Components of the Hematopoietic Stem Cell Niche. J Clin Med 2019, 8:707. doi: 10.3390/jcm8050707

Konieczny J, Arranz L. Updates on old and weary haematopoiesis. Int J Mol Sci 2018, 19:2567. doi: 10.3390/ijms19092567

Grimolizzi F, Arranz L. Multiple faces of succinate beyond metabolism in blood. Haematologica 2018, 103:1586–1592. doi: 10.3324/haematol.2018.196097

Bernal A, Arranz L. Nestin-expressing progenitor cells: function, identity and therapeutic implications. Cell Mol Life Sci 2018, 75:2177–2195. doi: 10.1007/s00018-018-2794-z 

*Arranz L, Arriero MM, Villatoro A. Interleukin-1β as emerging therapeutic target in hematological malignancies and potentially in their complications. Blood Rev 2017, 31:306-317.  doi: 10.1016/j.blre.2017.05.001. *Corresponding author

Sánchez-Aguilera A, Arranz L, Martín-Pérez D, García-García A, Stavropoulou V, Kubovcakova L, Isern J, Martín-Salamanca S, Langa X, Skoda RC, Schwaller J, Méndez-Ferrer S. Estrogen Signaling Selectively Induces Apoptosis of Hematopoietic Progenitors and Myeloid Neoplasms without Harming Steady-State Hematopoiesis. Cell Stem Cell 2014, 15:791-804.

Isern J, García-García A, Martín AM, Arranz L, Martín-Pérez D, Torroja C, Sánchez-Cabo F, Méndez-Ferrer S. The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem-cell-niche function. eLife 2014, 10.7554/eLife.03696.

Arranz L, Sánchez-Aguilera A, Martín-Pérez D, Isern J, Langa X, Tzankov A, Lundberg P, Muntión S, Tzeng Y-S, Lai D-M, Schwaller J, Skoda RC, Méndez-Ferrer S. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature 2014, 512:78-81.

Arranz L, Urbano-Ispizúa A, Méndez-Ferrer S. Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells. Haematologica 2013, 98:993-995.

Isern J, Martín-Antonio B, Ghazanfari R, Martín AM, del Toro R, Sánchez-Aguilera A, Arranz L, Martín-Pérez D, López JA, Suárez-Lledó M, Marín P, Van Pel M, Vázquez J, Fibbe WE, Scheding S, Urbano-Ispizúa A, Méndez-Ferrer S. Self-renewing human mesenspheres promote hematopoietic stem cell expansion. Cell Rep 2013, 3:1714-1724.

Arranz L, Méndez-Ferrer S. Network anatomy and in vivo physiology of mesenchymal stem cells. Inflamm Regen 2013, 33:38-47.

Arranz L, Naudí A, De la Fuente M, Pamplona R. Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage. Age (Dordr) 2013, 35:621-635.

Arranz L, De Castro NM, Baeza I, Giménez-Llort L, De la Fuente M. Effect of environmental enrichment on the immunoendocrine aging of male and female triple-transgenic 3xTg-AD mice for Alzheimer's disease. J Alzheimers Dis 2011, 25:727-737.

Arranz L, De Castro NM, Baeza I, Maté I, Viveros MP, De la Fuente M. Environmental enrichment improves age-related immune system impairment: long-term exposure since adulthood increases life span in mice. Rejuvenation Res 2010, 13:415-428. Erratum in: Rejuvenation Res 2010, 13:627.

Arranz L, Caamaño J, Lord JM, De la Fuente M. Preserved immune functions and controlled leucocyte oxidative stress in long-lived mice: possible role of nuclear factor-kappaB. J Gerontol A Biol Sci Med Sci 2010, 65:941-950.

Arranz L, Lord JM, De la Fuente M. Preserved ex vivo inflammatory status and cytokine responses in naturally long-lived mice. Age (Dordr) 2010, 32:451-466.

Arranz L, De Castro NM, Baeza I, De la Fuente M. Differential expression of Toll-like receptor 2 and 4 on peritoneal leukocyte populations from long-lived and non-selected old female mice. Biogerontology 2010, 11:475-482.

 

Book chapters

De la Fuente M, Arranz L. The importance of the environment in brain aging: Be happy, live longer! Brain Aging and Therapeutic Interventions 2013, pp: 79-94. doi: 10.1007/978-94-007-5237-5_6