Bilde av Brox, Jan
Bilde av Brox, Jan
Adjunct Professor Department of Medical Biology jbr001@post.uit.no Tromsø

Jan Brox


Job description

Positions/present employment       

Professor II in medical biochemistry, Department of Medical Biology, University of Tromsø

Member of Hematological Research Group

Member of the Scientific Board of the Tromsø Study no 6

Senior consultant in Medical biochemistry, University Hospital of North-Norway (main position) Division of Diagnostic Services , member of the Division`s leaderteam,University Hospital of North-Norway, Department ofLaboratory Medicine, member of the Department`s leaderteam, University Hospital of North-Norway


  • Anne-Lise Bjørke Monsen, Kristin Varsi, Sandra Huber, Maria Averina, Bjørn Bolann, Jan Brox :
    PFAS exposure is associated with an unfavourable metabolic profile in infants six months of age
    Environment International 2024 DOI / ARKIV
  • Sandra Huber, Jörg Michel, Maurice Reijnen, Maria Averina, Bjørn Bolann, Jon Øyvind Odland et al.:
    A Fast-Forward Dilute-and-Shoot Multielement Method for Analysis of 33 Elements in Human Whole Blood, Serum, and Urine by Inductively Coupled Plasma Mass Spectrometry: A Streamlined Approach for Clinical Diagnostic and Biomonitoring
    Journal of Analytical Methods in Chemistry 2024 DOI / ARKIV
  • Maria Averina, Sandra Huber, Bjørg Almås, Jan Brox, Bjarne K. Jacobsen, Anne-Sofie Furberg et al.:
    Early menarche and other endocrine disrupting effects of per- and polyfluoroalkyl substances (PFAS) in adolescents from Northern Norway. The Fit Futures study
    Environmental Research 2023 DOI / ARKIV
  • Arntraut Götsch, Maria Averina, Jan Brox, Sandra Huber :
    Investigation of background contribution from different solvent brands used for sample preparation and analysis of persistent organic pollutants
    Organohalogen Compounds 2023 ARKIV
  • Maria Averina, Michael Stylidis, Jan Brox, Henrik Schirmer :
    NT-ProBNP and high-sensitivity troponin T as screening tests for subclinical chronic heart failure in a general population
    ESC Heart Failure 2022 DOI / ARKIV
  • Emmanuel Dartey, Dag Ellingsen, Balazs Berlinger, Yngvar Thomassen, Jon Øyvind Odland, Jan Brox et al.:
    Per- and Polyfluoroalkyl Substances in Human Serum Samples of Selected Populations from Ghana
    International Journal of Environmental Research and Public Health (IJERPH) 2021 DOI / ARKIV
  • Kristin Varsi, Ingrid Kristin Torsvik, Sandra Huber, Maria Averina, Jan Brox, Anne-Lise Bjørke Monsen :
    Impaired gross motor development in infants with higher PFAS concentrations
    Environmental Research 2021 DOI / ARKIV
  • Maria Averina, Jan Brox, Sandra Huber, Anne-Sofie Furberg :
    Exposure to perfluoroalkyl substances (PFAS) and dyslipidemia, hypertension and obesity in adolescents : the Fit Futures study
    Environmental Research 2021 DOI / ARKIV / FULLTEKST
  • Kristin Varsi, Sandra Huber, Maria Averina, Jan Brox, Anne-Lise Bjørke Monsen :
    Quantitation of linear and branched perfluoroalkane sulfonic acids (PFSAs) in women and infants during pregnancy and lactation
    Environment International 2021 DOI / ARKIV / FULLTEKST
  • Anne Lise Bjørke Monsen, Kristin Varsi, Maria Averina, Jan Brox, Sandra Huber :
    Perfluoroalkyl substances (PFASs) and mercury in never-pregnant women of fertile age: association with fish consumption and unfavorable lipid profile
    BMJ Nutrition, Prevention and Health 2020 DOI / ARKIV
  • Sandra Huber, Maria Averina, Jan Brox :
    Automated sample preparation and GC-API-MS/MS as a powerful tool for analysis of legacy POPs in human serum and plasma
    Analytical Methods 2020 DOI
  • Thea Anine Strøm Halden, Kine Eide Kvitne, Karsten Midtvedt, Laavanyaah Rajakumar, Ida Robertsen, Jan Brox et al.:
    Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus
    Diabetes Care 2019 DOI / ARKIV
  • Maria Averina, Jan Brox, Sandra Huber, Anne-Sofie Furberg, Martin Sørensen :
    Serum perfluoroalkyl substances (PFAS)and risk of various allergies in adolescents. The Tromsø study Fit Futures in Northern Norway
    Environmental Research 2019 DOI / ARKIV
  • Maria Averina, Jan Brox, Sandra Huber, Anne-Sofie Furberg :
    Perfluoroalkyl substances in adolescents in northern Norway: Lifestyle and dietary predictors. The Tromsø study, Fit Futures 1
    Environment International 2018 DOI
  • Gro Grimnes, Trond Isaksen, Ynse Ieuwe Gerardus Vladimir Tichelaar, Jan Brox, Sigrid Kufaas Brækkan, John-Bjarne Hansen :
    C-reactive protein and risk of venous thromboembolism: Results from a population-based case-crossover study
    Haematologica 2018 DOI / ARKIV
  • Gunhild Lerstad, Ellen Elisabeth Brodin, Johan Svartberg, Rolf Jorde, Jan Brox, Sigrid Kufaas Brækkan et al.:
    Associations between serum levels of calcium, parathyroid hormone and future risk of venous thromboembolism: The Tromsø study
    European Journal of Endocrinology (EJE) 2017 DOI
  • Anders Vik, Ellen Elisabeth Brodin, Ellisiv B. Mathiesen, Jan Brox, Lone Jørgensen, Inger Njølstad et al.:
    Serum osteoprotegerin and renal function in the general population: The Troms? Study
    Clinical Kidney Journal (CKJ) 2017 DOI / ARKIV
  • Emmanuel Dartey, Balazs Berlinger, Stephan Weinbruch, Yngvar Thomassen, Jon Øyvind Odland, Jan Brox et al.:
    Essential and non-essential trace elements among working populations in Ghana
    Journal of Trace Elements in Medicine and Biology 2017 DOI / ARKIV
  • Jon Martin Arnemo, Maria Averina, Anne-Lise Bjørke Monsen, Bjørn Bolann, Jan Brox, Merete Eggesbø et al.:
    Bly fra ammunisjon skader folkehelsen
    Tidsskrift for Den norske legeforening (Tidsskriftet) 2025 DOI
  • Maria Averina, Sandra Huber, Jan Brox, Merete Eggesbø, Anne-Lise Bjørke Monsen :
    High serum concentrations of perfluoroalkyl- and polyfluoroalkyl substances (PFAS) in Norwegian children and associations with adverse health effects
    2025
  • Maria Averina, Sandra Huber, Jan Brox, Mette Kjær, Bjørn Bolann :
    Lead, mercury, polychlorinated biphenyls (PCBs) and per- and polyfluoroalkyl substances (PFAS) in blood donors - The multicenter Norwegian donor study
    2025
  • Maria Averina, Sandra Huber, Jan Brox, Mette Kjær, Bjørn Bolann :
    Lead, mercury, polychlorinated biphenyls (PCBs) and per- and polyfluoroalkyl substances (PFAS) in blood donors - The multicenter Norwegian donor study
    2024
  • Anne-Lise Bjørke Monsen, Maria Averina, Ingrid Hokstad, Merete Åse Eggesbø, Sandra Huber, Bjørn Bolann et al.:
    Interessegruppe for miljøgifter og folkehelse
    Tidsskrift for Den norske legeforening (Tidsskriftet) 2024 DOI
  • Sandra Huber, Maria Averina, Marit Nøst Hegseth, Jan Brox :
    Analysis of Hydroxylated Polycyclic Aromatic Hydrocarbons, Cotinine, and Creatinine by Convergence Chromatography Tandem Mass-Spectrometry
    2024
  • Maria Averina, Sandra Huber, Jan Brox, Mette Kjær, Bjørn Bolann :
    Lead, mercury, polychlorinated biphenyls (PCBs) and per- and polyfluoroalkyl substances (PFAS) in blood donors - The multicenter Norwegian donor study
    2024
  • Bjørn Bolann, Anne-Lise Bjørke Monsen, Maria Averina, Jan Brox, Merete Åse Eggesbø, Ingrid Hokstad et al.:
    Helsefarlige stoffer på avveie
    2024 DOI
  • Bjørn J. Bolann, Sandra Huber, Maria Averina, Merete Åse Eggesbø, Ingrid Hokstad, Jan Brox et al.:
    Bør vi spise mer fisk – eller mindre?
    2023 DOI / ARKIV / FULLTEKST
  • Arntraut Götsch, Maria Averina, Jan Brox, Sandra Huber :
    Investigation of background contribution from different solvent brands used for sample preparation and analysis of persistent organic pollutants
    2023
  • Maria Averina, Sandra Huber, Jan Brox, Mette Kjær, Bjørn Bolann :
    Environmental pollutants in blood donors - The multicenter Norwegian donor study
    2023
  • Sandra Huber, Maria Averina, Bjørn Bolann, Solrunn Hansen, Jon Øyvind Odland, Jan Brox :
    A fast forward dilute and shoot multi-element method for analysis of heavy metals and trace elements in whole blood, serum and urine by inductively coupled plasma mass spectrometry for clinical diagnostic and biomonitoring
    2023
  • Maria Averina, Anne-Lise Bjørke Monsen, Bjørn Johan Bolann, Jan Brox, Merete Eggesbø, Ingrid Hokstad et al.:
    Høyt nivå av tungmetaller i krabbe
    2022 DOI / ARKIV
  • Jan Brox, Sandra Huber :
    Miljøgiftlaboratoriet ved UNN og vår forskningsaktivitet
    2022
  • Sandra Huber, Maria Averina, Jan Brox :
    Automated sample preparation and atmospheric pressure GC-MS/MS as a powerful tool for analysis of legacy POPs in human serum and plasma
    2021
  • Sandra Huber, Maria Averina, Jan Brox :
    The Environmental Pollutant Laboratory - State of the Art Research on Human Health Effects Related to Contaminants
    2021
  • Sandra Huber, Maria Averina, Jan Brox :
    The Environmental Pollutant Laboratory - State of the Art Research on Human Health Effects Related to Contaminants
    2021
  • Jan Brox, Maria Averina, Sandra Huber :
    Kan miljøgifter true oss som art?
    Tidsskrift for Den norske legeforening (Tidsskriftet) 2020 DOI
  • Kjetil Østli, Merete Åse Eggesbø, Jan Brox, Sandra Huber :
    Vi er marinert i miljøgifter. Hva gjør det med oss?
    20. June 2019
  • Maria Averina, Sandra Huber, Jan Brox :
    Health effects of perfluoroalkyl substances in Norwegian adolescents recruited from the general population in Northern Norway.
    2019
  • Sandra Huber, Maria Averina, Jan Brox :
    Automated sample preparation and atmospheric pressure GC-MS/MS as a powerful tool for analysis of legacy POPs in human serum and plasma
    2019
  • Jan Brox, Maria Averina, Sandra Huber, Jan Eskil Severinsen :
    Unik miljøgiftsatsing i nord
    30. April 2019
  • Maria Averina, Jan Brox, Sandra Huber, Bjørn Johan Bolann :
    Helseeffekter av miljøgifter.
    2019
  • Sandra Huber, Jon Øyvind Odland, Maria Averina, Jan Brox :
    Befolkningsundersøkelser i nord - miljøgifter
    2018
  • Sandra Huber, Jon Øyvind Odland, Maria Averina, Jan Brox :
    Befolkningsundersøkelser i nord - miljøgifter
    2018
  • Sandra Huber, Jon Øyvind Odland, Maria Averina, Jan Brox :
    Befolkningsundersøkelser i nord - miljøgifter
    2018
  • Sandra Huber, Maria Averina, Jan Brox :
    An automated high-throughput sample preparation method for analysis of legacy POPs in human serum and plasma by APGC-MS/MS
    2018
  • Bjørn Johan Bolann, Sandra Huber, Jérôme Ruzzin, Jan Brox, Henrik Huitfeldt, Anne Lise Bjørke Monsen :
    Er miljøgifter i norsk kosthold skadelig for barn?
    2017 DOI
  • Maria Averina, Sandra Huber, Jan Brox, Anne-Sofie Furberg :
    Serum perfluoroalkyl substances (PFAS) in schoolchildren from northern Norway: Dietary impact
    2017
  • Sandra Huber, Maria Averina, Inger Njølstad, Anne-Sofie Furberg, Bjørn Johan Bolann, Mette Kjær et al.:
    Perfluoroalkyl substances in different cohorts from North Norway
    2017
  • Jan Brox, Sandra Huber :
    Etterlyser mer forskning på hvordan miljøgifter påvirker barn
    27. February 2017
  • Bjørn Johan Bolann, Sandra Huber, Jérôme Ruzzin, Jan Brox, Henrik Huitfeldt, Anne Lise Bjørke Monsen :
    Miljøgifter i kosten handler om mer enn fisk
    Tidsskrift for Den norske legeforening (Tidsskriftet) 2017 DOI

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    Research interests

    Current research interests 

    Arterial and venous thromboembolism, risk factors, cell signalling and pathobiochemistry.

    Environmental pollution and human health.


    CV

    Academic degree

    1979                Cand.med. (MD), University of Tromsø

    1985                Dr. med (PhD in cardiovascular medicine) University of Tromsø

    1988                MPH (Master of Public Health) University of Tromsø

     

    Previous academic positions 

    1979-82           Research fellow, Univ. of Tromsø .

    1987-2002       Associate professor in Medical biochemistry, University of Tromsø (20%)

    2002-               Professor II in Medical biochemistry, University of Tromsø (20% position)

     

    Publications

    60 original full papers in peer-reviewed journals listed in PubMed. Various abstracts  presented at and published in conjunction with scientific international meetings/conferences.

     

    Supervision of students

    Supervision/ co-supervision of master, PhD and post-doc students.