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Research interests
The main focus of my research is permeability of drug through and into different absorption barriers, both in respect of understanding the mechanisms and factors affecting the permeability of compounds, and means to improve the permeability through use of advanced delivery systems. I have, in particular, experience with Advanced nanoparticulate drug delivery systems mainly for poorly soluble drugs as well as use of liposomes as model for cell membranes in interactions with peptides and proteins. My expertise thus spans from development of models for permeability screening as well as estimation of permeability of drugs and drug candidates, formulation of poorly soluble drugs, characterization of nanoparticulate delivery systems, biopharmaceutical characterisation of delivery systems (cell toxicity and permeability) to in vivo biodistribution studies in mouse models. Administration sites in focus have been the intestine, vagina, and skin, but I have also experience with parenteral formulations for tumour targeted delivery.
List of areas of research interests:
- Permeability through biological barriers (watch movie to learn more).
- The phospholipid vesicle-based permeation assay (PVPA)
- Liposomes as drug carriers
- Liposomes as model systems for cells and bacteria in interaction studies
- Delivery of lipophilic drug compounds
Dissemination to sosiety availeble online
Sjekk datoen, (2023)
Forskningspodcast fra UiT Norges arktiske universitet (2018)
Hvordan velge de beste kandidatene for fremtidens legemidler? (2018)
42 millioner kroner for utvikling av persontilpasset medisin (2018)
Så lenge holder solkremen din (2017)
Er det sant at man må kaste solkremen etter ett år? (2016)
Skammelig nedprioritering (2016)
Er kvinnesykdommer mindre viktige? (2016)
Skammelig nedprioritering av forskning på kvinnesykdommer (2016)
Finner de beste legemidlene – uten dyreforsøk (2015)
Gjennombrudd: Dyreforsøk med brannskader kan erstattes (2014)
Hermer stoffopptak via hud og tarm (2012)
Legemidler og barrierer (2012)
Teaching
I am teaching in the following subjects:
FAR-1101 Farmasi grunnemne
FAR-1401 Fysikalsk farmasi (emneleder)
FAR-2401 Basal legemiddelproduksjon
FAR-2402 Legemiddelformulering og biofarmasi
FAR-3401 Avansert legemiddelteknologi og biofarmasi
FAR-3043 Masteremne i nanoteknologi
FAR-8043 PhD-emne i nanomedisin
