Gevorgyan Lab

Publications

 

 

25. Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impuritie

A. Gevorgyan,* K. H. Hopmann, A. Bayer, Organometallics 2022, 41, 1777-1785.

Highlighted in C2W news magazine of the Royal Netherlands Chemical Society (KNCV) as a new promising direction in green chemistry!


24. Lipids as Versatile Solvents for Chemical Synthesis

A. Gevorgyan,* K. H. Hopmann, A. Bayer, Green Chem. 2021, 23, 7219-7227.

Highlighted in Chemistry World news magazine of the Royal Society of Chemistry (RSC) as a new promising direction in green chemistry!

Highlighted in C2W news magazine of the Royal Netherlands Chemical Society (KNCV) as a new promising direction in green chemistry!


23. Computational and Experimental Insights into Asymmetric Rh-Catalyzed Hydrocarboxylation with CO2

L. Pavlovic, M. Pettersen, A. Gevorgyan, J. Vaitla, A. Bayer,* K. H. Hopmann,* Eur. J. Org. Chem. 2021, 663-670.


22. Renewable Solvents for Palladium-Catalyzed Carbonylation Reactions

A. Ismael, A. Gevorgyan, T. Skrydstrup, A. Bayer,* Org. Process Res. Dev. 2020, 24, 2665-2675.


21. Formal C‐H Carboxylation of Unactivated Arenes

A. Gevorgyan,* K. H. Hopmann, A. Bayer,* Chem. Eur. J. 2020, 26, 6064-6069.

Highlighted in Org. Chem. Highlights, as a unique concept for selective functionalization of benzenes!


20. Exploration of New Biomass-Derived Solvents: Application to Carboxylation Reactions

A. Gevorgyan,* K. H. Hopmann, A. Bayer,* ChemSusChem 2020, 13, 2080-2088.


19. Mechanistic Insights into Copper-Catalyzed Carboxylations

M. F. Obst, A. Gevorgyan, A. Bayer,* K. H. Hopmann,* Organometallics 2020, 39, 1545-1552.


18. Caesium Fluoride-Mediated Hydrocarboxylation of Alkenes and Allenes: Scope and Mechanistic Insights

A. Gevorgyan, M. F. Obst, Y. Guttormsen, F. Maseras, K. H. Hopmann,* A. Bayer,* Chem. Sci. 2019, 10, 10072-10078.


17. Application of Silicon-Initiated Water Splitting for the Reduction of Organic Substrates

A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, V. O. Iaroshenko,* ChemPlusChem 2018, 83, 375-382.


16. Disilanes as oxygen scavengers and surrogates of hydrosilanes suitable for selective reduction of nitroarenes, phosphine oxides and other valuable substrates

A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, V. O. Iaroshenko,* Org. Chem. Front. 2017, 4, 2437-2444.


Publications prior postdoctoral studies: 

15. Sonogashira reaction of 5-substituted 3-(prop-2-yn-1-yl)oxolan-2-ones

T. V. Ghochikyan, M. A. Samvelyan,* A. S. Galstyan, A. Gevorgyan, G. Vardanyan, T. Grigoryan, P. Langer, Russ. J. Organ. Chem. 2017, 53:12, 1833-1839.


14. Synthesis of Alkynylated Dihydrofuran-2(3H)-ones as Potent and Selective Inhibitors of Tissue Non-Specific Alkaline Phosphatase

A. Petrosyan, T. V. Ghochikyan, S. A. Ejaz, Z. Z. Mardiyan, S. U. Khan, T. Grigoryan, A. Gevorgyan, M. A. Samvelyan, A. S. Galstyan, S. Parpart, Q. Rahman, J. Iqbal, P. Langer,* ChemistrySelect 2017, 2, 5677-5683.


13. Synthesis of 4-quinolones, benzopyran derivatives and other fused systems based on the domino ANRORC reactions of (ortho-fluoro)-3-benzoylchromones

V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, T. Grigoryan, A. Villinger, P. Langer,* RSC Adv. 2015, 5, 28717-28724.


12. Transition-metal-catalyzed arylation of nitroimidazoles and further transformations of manipulable nitro group

V. O. Iaroshenko,* A. Gevorgyan, S. Mkrtchyan, K. Arakelyan, T. Grigoryan, J. Yedoyan, A. Villinger, P. Langer,* J. Org. Chem. 2015, 80, 2103-2119.


11. Regioselective direct arylation of fused 3-nitropyridines and other nitro-substituted heteroarenes: the multipurpose nature of the nitro group as a directing group

V. O. Iaroshenko,* A. Gevorgyan, S. Mkrtchyan, T. Grigoryan, E. Movsisyan, A. Villinger, P. Langer,* ChemCatChem 2015, 7, 316-324.


10. Regioselective and guided C-H activation of 4-nitropyrazoles

V. O. Iaroshenko,* A. Gevorgyan, O. Davydova, A. Villinger, P. Langer,* J. Org. Chem. 2014, 79, 2906-2915.

Highlighted in the ACS Select Virtual Issue on recent discoveries that illuminate current trends and inspiring discoveries in C-H Functionalization.


9. Efficient synthesis of novel benzo[b][1,8]naphthyridin-4(1H)-ones and pyrido[2,3-b]quinoxalin-4(1H)-ones from alkynones and primary amines

V. O. Iaroshenko,* M. Zahid, S. Mkrtchyan, A. Gevorgyan, K. Altenburger, I. Knepper, A. Villinger, V. Y. Sosnovskikh, P. Langer, Tetrahedron 2013, 69, 2309-2318.


8. Design, synthesis and transformation of some heteroannulated 3-aminopyridines-purine isosteres with exocyclic nitrogen atom

V. O. Iaroshenko,* M. Vilches-Herrera, A. Gevorgyan, S. Mkrtchyan, K. Arakelyan, D. Ostrovskyi, M. S. A. Abbasi, L. Supe, A. Hakobyan, A. Villinger, D. M. Volochnyuk, A. Tolmachev, Tetrahedron 2013, 69, 1217-1228.


7. Asymmetric synthesis of enantiomerically enriched (S)-α-aminopropionic acids containing heterocyclic side chains

A. S. Saghyan,* G. M. Mkrtchyan, A. S. Dadayan, S. G. Petrosyan, A. V. Geolchanyan, H. M. Simonyan, A. F. Mkrtchyan, S. Mkrtchyan, A. Gevorgyan, V. O. Iaroshenko, P. Langer,* Tetrahedron: Asymmetry 2013, 24, 229-232.


6. 2,3-Unsubstituted chromones and their enaminone precursors as versatile reagents for the synthesis of fused pyridines

V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, M. Miliutina, A. Villinger, D. Volochnyuk, V. Y. Sosnovskikh, P. Langer,* Org. Biomol. Chem. 2012, 10, 890-894.


5. Synthesis of heteroannulated 3-nitro- and 3-aminopyridines by cyclocondensation of electron-rich aminoheterocycles with 3-nitrochromone

V. O. Iaroshenko,* S. Mkrtchyan, A. Gevorgyan, M. Vilches-Herrera, D. V. Sevenard, A. Villinger, T. V. Ghochikyan, A. Saghiyan, V. Y. Sosnovskikh, P. Langer,* Tetrahedron 2012, 68, 2532-2543.


4. Design and synthesis of condensed thienocoumarins by Suzuki-Miyaura reaction/lactonization tandem protocol

V. O. Iaroshenko,* S. Ali, S. Mkrtchyan, A. Gevorgyan, T. M. Babar, V. Semeniuchenko, Z. Hassan, A. Villinger, P. Langer, Tetrahedron Lett. 2012, 53, 7135-7139.


3. Asymmetric synthesis of new β-heterocyclic (S)-α-aminopropionic acids

A. S. Saghyan,* H. M. Simonyan, L. A. Stepanyan, S. G. Ghazaryan, A. V. Geolchanyan, L. L. Manasyan, V. T. Ghochikyan, T. V. Ghochikyan, N. A. Hovhannisyan, A. Gevorgyan, V. O. Iaroshenko, P. Langer,* Tetrahedron: Asymmetry 2012, 23, 891-897.


2. 3-Methoxalylchromone-a novel versatile reagent for the regioselective purine isostere synthesis

S. Mkrtchyan, V. O. Iaroshenko,* S. Dudkin, A. Gevorgyan, M. Vilches-Herrera, G. Ghazaryan, D. M. Volochnyuk, D. Ostrovskyi, Z. Ahmed, A. Villinger, V. Y. Sosnovskikh, P. Langer,* Org. Biomol. Chem. 2010, 8, 5280-5284.


1. Synthesis of chromeno[3,4-b]pyrrol-4(3H)-ones by cyclocondensation of 1,3-bis(trimethylsilyloxy)buta-1,3-dienes with 4-chloro-3-nitrocoumarin

O. Fatunsin, V. O. Iaroshenko,* S. Dudkin, M. Shkoor, D. Volochnyuk, A. Gevorgyan, P. Langer,* Synlett 2010, 1533-1535.