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Associate Professor

Kilvær, Thomas Karsten

Department of Clinical Medicine
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  • Selven, Hallgeir; Rasmussen Busund, Lill-Tove; Bremnes, Roy M.; Andersen, Sigve; Kilvær, Thomas Karsten. High expression of microRNA‑126 relates to favorable prognosis for colon cancer patients. Scientific Reports 2021. ISSN 2045-2322.s doi: 10.1038/s41598-021-87985-3.

  • Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Andersen, Sigve; Rakaee, Mehrdad; Bremnes, Roy M.; Rasmussen Busund, Lill-Tove; Dønnem, Tom. Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?. Carcinogenesis 2020; Volum 41 (12). ISSN 0143-3334.s 1671 - 1681.s doi: 10.1093/carcin/bgaa105.

  • Rakaee, Mehrdad; Busund, Lill-Tove; Jamaly, Simin; Paulsen, Erna-Elise; Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Bremnes, Roy M.; Dønnem, Tom; Kilvær, Thomas Karsten. Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry. Neoplasia 2019; Volum 21 (3). ISSN 1522-8002.s 282 - 293.s doi: 10.1016/j.neo.2019.01.005.

  • Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Vik, Jørg; de Petris, Luigi; Dønnem, Tom; Strell, Carina; Østman, Arne; Rasmussen Busund, Lill-Tove; Martinez, Inigo Zubiavrre. Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC. Scientific Reports 2019; Volum 9:10163. ISSN 2045-2322.s 1 - 11.s doi: 10.1038/s41598-019-46510-3.

  • Kilvær, Thomas Karsten; Rakaee, Mehrdad; Hellevik, Turid; Östman, Arne; Strell, Carina; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer. PLOS ONE 2018; Volum 13 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0192157.

  • Rakaee, Mehrdad; Kilvær, Thomas Karsten; Dalen, Stig Manfred; Richardsen, Elin; Paulsen, Erna Elise; Hald, Sigurd; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove. Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer. Human Pathology 2018; Volum 79. ISSN 0046-8177.s 188 - 198.s doi: 10.1016/j.humpath.2018.05.017.

  • Skjefstad, Kaja Konstanse; Johannessen, Charles; Grindstad, Thea K.W.; Kilvær, Thomas Karsten; Paulsen, Erna Elise; Pedersen, Mona Irene; Dønnem, Tom; Andersen, Sigve; Bremnes, Roy M.; Richardsen, Elin; Al-Saad, Samer; Busund, Lill-Tove. A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer. Scientific Reports 2018; Volum 8. ISSN 2045-2322.s doi: 10.1038/s41598-018-26864-w.

  • Hald, Sigurd; Rakaee, Mehrdad; Martinez, Inigo Zubiavrre; Richardsen, Elin; Al-Saad, Samer; Paulsen, Erna Elise; Blix, Egil Støre; Kilvær, Thomas Karsten; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival. Clinical Lung Cancer 2018; Volum 19 (3). ISSN 1525-7304.s 249 - 259.e2.s doi: 10.1016/j.cllc.2017.12.001.

  • Al-Saad, Samer; Richardsen, Elin; Kilvær, Thomas Karsten; Dønnem, Tom; Andersen, Sigve; Rakaee, Mehrdad; Bremnes, Roy M.; Busund, Lill-Tove. The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer. PLOS ONE 2017; Volum 12:e0181527 (7). ISSN 1932-6203.s 1 - 20.s doi: 10.1371/journal.pone.0181527.

  • Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaee, Mehrdad; Richardsen, Elin; Hald, Sigurd; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases. Cancer Immunology and Immunotherapy 2017; Volum 66. ISSN 0340-7004.s 1449 - 1461.s doi: 10.1007/s00262-017-2039-2.

  • Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Richardsen, Elin; Paulsen, Erna-Elise; Hald, Sigurd; Al-Saad, Samer; Brustugun, Odd Terje; Helland, Åslaug; Lund-Iversen, Marius; Solberg, Steinar; Grønberg, Bjørn Henning; Wahl, Sissel Gyrid Freim; Helgeland, Lars; Fløtten, Øystein; Pohl, M; Al-Shibli, Khalid; Sandanger, Torkjel M; Pezzella, Francesco; Busund, Lill-Tove; Bremnes, Roy M.. Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer. Annals of Oncology 2016; Volum 27 (2). ISSN 0923-7534.s 225 - 232.s doi: 10.1093/annonc/mdv560.

  • Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaee, Mehrdad; Al-Saad, Samer; Hald, Sigurd; Andersen, Sigve; Richardsen, Elin; Ness, Nora; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. Assessing PDL-1 and PD-1 in non-small cell lung cancer: a novel immunoscore approach. Clinical Lung Cancer 2016; Volum 18 (2). ISSN 1525-7304.s 220 - 233.e8.s doi: 10.1016/j.cllc.2016.09.009.

  • Rakaee, Mehrdad; Busund, Lill-Tove; Paulsen, Erna-Elise; Richardsen, Elin; Al-Saad, Samer; Andersen, Sigve; Dønnem, Tom; Bremnes, Roy M.; Kilvær, Thomas Karsten. Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer. OncoTarget 2016; Volum 7 (44). ISSN 1949-2553.s 72184 - 72196.s doi: 10.18632/oncotarget.12360.

  • Bremnes, Roy M.; Busund, Lill-Tove; Kilvær, Thomas Karsten; Andersen, Sigve; Richardsen, Elin; Paulsen, Erna-Elise; Hald, Sigurd; Rakaee, Mehrdad; Cooper, Wendy A.; Kao, Steven C.; Dønnem, Tom. The role of tumor-infiltrating lymphocytes in development, progression, and prognosis of non-small cell lung cancer. Journal of Thoracic Oncology 2016; Volum 11 (6). ISSN 1556-0864.s 789 - 800.s doi: 10.1016/j.jtho.2016.01.015.

  • Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Rakaee, Mehrdad; Al-Saad, Samer; Johansen Maurseth, Ramona; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival. British Journal of Cancer 2016; Volum 114 (10). ISSN 0007-0920.s 1145 - 1151.s doi: 10.1038/bjc.2016.92.

  • Skjefstad, Kaja; Grindstad, Thea; Rakaee, Mehrdad; Richardsen, Elin; Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer. Steroids 2016; Volum 113. ISSN 0039-128X.s 5 - 13.s doi: 10.1016/j.steroids.2016.05.008.

  • Dønnem, Tom; Hald, Sigurd; Paulsen, Erna-Elise; Richardsen, Elin; Al-Saad, Samer; Kilvær, Thomas Karsten; Brustugun, Odd Terje; Helland, Åslaug; Lund-Iversen, Marius; Poehl, Mette; Olsen, Karen Ege; Ditzel, Henrik J.; Hansen, Olfred; Al-Shibli, Khalid; Kiselev, Yury; Sandanger, Torkjel M; Andersen, Sigve; Pezzella, Francesco; Bremnes, Roy M.; Busund, Lill-Tove. Stromal CD8+ T-cell density - A promising supplement to TNM staging in non-small cell lung cancer. Clinical Cancer Research 2015; Volum 21 (11). ISSN 1078-0432.s 2635 - 2643.s doi: 10.1158/1078-0432.CCR-14-1905.

  • Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Hald, Sigurd; Wilsgaard, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Lymphangiogenic markers and their impact on nodal metastasis and survival in non-small cell lung cancer - A structured review with meta-analysis. PLOS ONE 2015; Volum 10:e0132481 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0132481.

  • Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Johansen Maurseth, Ramona; Al-Saad, Samer; Hald, Sigurd; Al-Shibli, Khalid; Andersen, Sigve; Richardsen, Elin; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. CD45RO+ memory T lymphocytes – a candidate marker for TNM-immunoscore in squamous non-small cell lung cancer. Neoplasia 2015; Volum 17 (11). ISSN 1522-8002.s 839 - 848.s doi: 10.1016/j.neo.2015.11.004.

  • Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Hellevik, Turid; Al-Saad, Samer; Paulsen, Erna-Elise; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre. Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers. PLOS ONE 2015; Volum 10:e0134965 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0134965.

  • Hald, Sigurd; Kiselev, Yury; Al-Saad, Samer; Richardsen, Elin; Johannessen, Charles; Eilertsen, Marte; Kilvær, Thomas Karsten; Al-Shibli, Khalid; Andersen, Sigve; Busund, Lill-Tove; Bremnes, Roy M.; Dønnem, Tom. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: Combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 2015; Volum 15 (441). ISSN 1471-2407.s doi: 10.1186/s12885-015-1446-z.

  • Kilvær, Thomas Karsten; Smeland, Eivind; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk. (Fulltekst: http://www.biomedcentral.com/1472-6890/14/5 BMC Clinical Pathology 2014; Volum 14:5. ISSN 1472-6890.s doi: 10.1186/1472-6890-14-5.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas. (Fulltekst: http://www.biomedcentral.com/1472-6890/13/9/abstract BMC Clinical Pathology 2013; Volum 13 (9). ISSN 1472-6890.s doi: 10.1186/1472-6890-13-9.

  • Smeland, Eivind; Kilvær, Thomas Karsten; Sørbye, Sveinung Wergeland; Valkov, Andrey Yurjevich; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Prognostic Impacts of Hypoxic Markers in Soft Tissue Sarcoma. Sarcoma 2012; Volum 2012. ISSN 1357-714X.s doi: 10.1155/2012/541650.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic Impact of Jab1, p16, p21, p62, Ki67 and Skp2 in Soft Tissue Sarcomas. (Fulltekst: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0047068 PLOS ONE 2012; Volum 7 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0047068.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas. (Fulltekst: http://www.biomedcentral.com/1472-6890/12/5 BMC Clinical Pathology 2012; Volum 12 (5). ISSN 1472-6890.s doi: 10.1186/1472-6890-12-5.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas. (Fulltekst: http://www.biomedcentral.com/1472-6890/12/7/abstract BMC Clinical Pathology 2012; Volum 12 (7). ISSN 1472-6890.s doi: 10.1186/1472-6890-12-7.

  • Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. The Prognostic Impact of TGF-beta 1, Fascin, NF-kappa B and PKC-zeta Expression in Soft Tissue Sarcomas. PLOS ONE 2011; Volum 6 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0017507.

  • Valkov, Andrey Yurjevich; Kilvær, Thomas Karsten; Sørbye, Sveinung Wergeland; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. Journal of Translational Medicine 2011; Volum 9:200. ISSN 1479-5876.s doi: 10.1186/1479-5876-9-200.

  • Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom. Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients. Journal of Translational Medicine 2011; Volum 9. ISSN 1479-5876.s doi: 10.1186/1479-5876-9-104.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. Prognostic Impact of Lymphocytes in Soft Tissue Sarcomas. PLOS ONE 2011; Volum 6 (1). ISSN 1932-6203.s doi: 10.1371/journal.pone.0014611.

  • Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. Estrogen receptor and progesterone receptor are prognostic factors in soft tissue sarcomas. International Journal of Oncology 2011; Volum 38 (4). ISSN 1019-6439.s 1031 - 1040.s doi: 10.3892/ijo.2011.920.

  • Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove Rasmussen; Dønnem, Tom. Profiling of VEGFs and VEGFRs as prognostic factors in soft tissue sarcoma: VEGFR-3 is an independent predictor of poor prognosis. PLOS ONE 2010; Volum 5 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0015368.

  • Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Dønnem, Tom; Smeland, Eivind; Bremnes, Roy M.; Busund, Lill-Tove. Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival. Sarcoma 2010. ISSN 1357-714X.s doi: 10.1155/2010/751304.

  • Skjefstad, Kaja Konstanse; Grindstad, Thea K.W.; Rakaee, Mehrdad; Richardsen, Elin; Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]. Steroids 2018; Volum 130. ISSN 0039-128X.s 36 - 37.s doi: 10.1016/j.steroids.2017.11.010.

  • Kiselev, Yury; Valkov, Andrey Yurjevich; Busund, Lill-Tove; Bremnes, Roy M.; Snapkov, Igor; Mikkola, Ingvild; Kilvær, Thomas Karsten; Sorbye, SW; Smeland, Eivind; Dønnem, Tom. Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival. American Association of Cancer Research Annual Conference 2014-04-06 - 2014-04-07 2014.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator. Oncoimmunology 2012; Volum 1 (1). ISSN 2162-4011.s 75 - 77.s doi: 10.4161/onci.1.1.17825.

  • Skjefstad, Kaja Konstanse; Grindstad, Thea K.W.; Rakaee, Mehrdad; Richardsen, Elin; Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Bremnes, Roy M.; Busund, Lill-Tove; Al-Saad, Samer. Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]. Steroids 2018; Volum 130. ISSN 0039-128X.s 36 - 37.s doi: 10.1016/j.steroids.2017.11.010.

  • Kiselev, Yury; Valkov, Andrey Yurjevich; Busund, Lill-Tove; Bremnes, Roy M.; Snapkov, Igor; Mikkola, Ingvild; Kilvær, Thomas Karsten; Sorbye, SW; Smeland, Eivind; Dønnem, Tom. Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival. American Association of Cancer Research Annual Conference 2014-04-06 - 2014-04-07 2014.

  • Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove. High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator. Oncoimmunology 2012; Volum 1 (1). ISSN 2162-4011.s 75 - 77.s doi: 10.4161/onci.1.1.17825.

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