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Department of Clinical Medicine thomas.k.kilvar@uit.no

Thomas Karsten Kilvær



  • Erna-Elise Paulsen, Sigve Andersen, Mehrdad Rakaee, Mona Irene Pedersen, Ana Paola Lombardi, Mette Pøhl et al.:
    Impact of microvessel patterns and immune status in NSCLC: a non-angiogenic vasculature is an independent negative prognostic factor in lung adenocarcinoma
    Frontiers in Oncology 2023 ARKIV / DOI
  • Mehrdad Rakaee, Sigve Andersen, K. Giannikou, Erna-Elise Paulsen, Thomas Karsten Kilvær, Lill-Tove Rasmussen Busund et al.:
    Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
    Annals of Oncology 2023 ARKIV / DOI
  • Hallgeir Selven, Lill-Tove Rasmussen Busund, Sigve Andersen, Mona Irene Pedersen, Ana Paola Lombardi, Thomas Karsten Kilvær :
    High Expression of IRS-1, RUNX3 and SMAD4 Are Positive Prognostic Factors in Stage I–III Colon Cancer
    Cancers 2023 ARKIV / DOI
  • Hallgeir Selven, Sigve Andersen, Mona Irene Pedersen, Ana Paola Lombardi, Lill-Tove Rasmussen Busund, Thomas Karsten Kilvær :
    High expression of miR-17-5p and miR-20a-5p predicts favorable disease-specific survival in stage I-III colon cancer
    Scientific Reports 2022 ARKIV / DOI
  • Nikita Shvetsov, Morten Grønnesby, Edvard Pedersen, Kajsa Møllersen, Lill-Tove Rasmussen Busund, Ruth Schwienbacher et al.:
    A Pragmatic Machine Learning Approach to Quantify Tumor-Infiltrating Lymphocytes in Whole Slide Images
    Cancers 2022 ARKIV / DOI
  • Maria Jenvin Støen, Sigve Andersen, Mehrdad Rakaee, Mona I. Pedersen, Lise Martine Ingebriktsen, Tom Dønnem et al.:
    Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study
    Cancers 2021 ARKIV / DOI
  • Maria Jenvin Støen, Sigve Andersen, Mehrdad Rakaee, Mona Irene Pedersen, Lise Martine Ingebriktsen, Roy M. Bremnes et al.:
    High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients
    Scientific Reports 2021 ARKIV / DOI
  • Hallgeir Selven, Lill-Tove Rasmussen Busund, Sigve Andersen, Roy M. Bremnes, Thomas Karsten Kilvær :
    High expression of microRNA‑126 relates to favorable prognosis for colon cancer patients
    Scientific Reports 2021 ARKIV / DOI
  • Mehrdad Rakaee, Thomas Karsten Kilvær, Simin Jamaly, Thomas Berg, Erna-Elise Paulsen, Marte Berglund et al.:
    Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
    British Journal of Cancer 2021 DOI
  • Thomas Karsten Kilvær, Erna-Elise Paulsen, Sigve Andersen, Mehrdad Rakaee, Roy M. Bremnes, Lill-Tove Rasmussen Busund et al.:
    Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
    Carcinogenesis 2020 ARKIV / DOI
  • Mehrdad Rakaee, Lill-Tove Busund, Simin Jamaly, Erna-Elise Paulsen, Elin Richardsen, Sigve Andersen et al.:
    Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry
    Neoplasia 12. February 2019 ARKIV / DOI
  • Thomas Karsten Kilvær, Mehrdad Rakaee, Turid Hellevik, Jørg Vik, Luigi de Petris, Tom Dønnem et al.:
    Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC
    Scientific Reports 2019 ARKIV / DOI
  • Kaja Konstanse Skjefstad, Charles Johannessen, Thea K.W. Grindstad, Thomas Karsten Kilvær, Erna Elise Paulsen, Mona Irene Pedersen et al.:
    A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer
    Scientific Reports 2018 ARKIV / DOI
  • Mehrdad Rakaee, Thomas Karsten Kilvær, Stig Manfred Dalen, Elin Richardsen, Erna Elise Paulsen, Sigurd Hald et al.:
    Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
    Human Pathology 2018 DOI
  • Thomas Karsten Kilvær, Mehrdad Rakaee, Turid Hellevik, Arne Östman, Carina Strell, Roy M. Bremnes et al.:
    Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
    PLOS ONE 2018 ARKIV / DOI
  • Sigurd Hald, Mehrdad Rakaee, Inigo Zubiavrre Martinez, Elin Richardsen, Samer Al-Saad, Erna Elise Paulsen et al.:
    LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
    Clinical Lung Cancer 2018 DOI
  • Erna-Elise Paulsen, Thomas Karsten Kilvær, Mehrdad Rakaee, Elin Richardsen, Sigurd Hald, Sigve Andersen et al.:
    CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
    Cancer Immunology and Immunotherapy 2017 ARKIV / DOI
  • Samer Al-Saad, Elin Richardsen, Thomas Karsten Kilvær, Tom Dønnem, Sigve Andersen, Mehrdad Rakaee et al.:
    The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer
    PLOS ONE 2017 ARKIV / DOI
  • Erna-Elise Paulsen, Thomas Karsten Kilvær, Mehrdad Rakaee, Samer Al-Saad, Sigurd Hald, Sigve Andersen et al.:
    Assessing PDL-1 and PD-1 in non-small cell lung cancer: a novel immunoscore approach
    Clinical Lung Cancer 2016 ARKIV / DOI
  • Tom Dønnem, Thomas Karsten Kilvær, Sigve Andersen, Elin Richardsen, Erna-Elise Paulsen, Sigurd Hald et al.:
    Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer
    Annals of Oncology 2016 DOI
  • Roy M. Bremnes, Lill-Tove Busund, Thomas Karsten Kilvær, Sigve Andersen, Elin Richardsen, Erna-Elise Paulsen et al.:
    The role of tumor-infiltrating lymphocytes in development, progression, and prognosis of non-small cell lung cancer
    Journal of Thoracic Oncology 2016 DOI
  • Kaja Skjefstad, Thea Grindstad, Mehrdad Rakaee, Elin Richardsen, Tom Dønnem, Thomas Karsten Kilvær et al.:
    Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer
    Steroids 2016 DOI
  • Thomas Karsten Kilvær, Erna-Elise Paulsen, Mehrdad Rakaee, Samer Al-Saad, Ramona Johansen Maurseth, Khalid Al-Shibli et al.:
    The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
    British Journal of Cancer 2016 ARKIV / DOI
  • Mehrdad Rakaee, Lill-Tove Busund, Erna-Elise Paulsen, Elin Richardsen, Samer Al-Saad, Sigve Andersen et al.:
    Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer
    OncoTarget 2016 ARKIV / DOI
  • Thomas Karsten Kilvær, Mehrdad Rakaeekhanehkenari, Turid Hellevik, Samer Al-Saad, Erna-Elise Paulsen, Roy M. Bremnes et al.:
    Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers
    PLOS ONE 2015 ARKIV / DOI
  • Thomas Karsten Kilvær, Erna-Elise Paulsen, Sigurd Hald, Tom Wilsgaard, Roy M. Bremnes, Lill-Tove Busund et al.:
    Lymphangiogenic markers and their impact on nodal metastasis and survival in non-small cell lung cancer - A structured review with meta-analysis
    PLOS ONE 2015 ARKIV / DOI
  • Erna-Elise Paulsen, Thomas Karsten Kilvær, Mehrdad Rakaeekhanehkenari, Ramona Johansen Maurseth, Samer Al-Saad, Sigurd Hald et al.:
    CD45RO+ memory T lymphocytes – a candidate marker for TNM-immunoscore in squamous non-small cell lung cancer
    Neoplasia 2015 ARKIV / DOI
  • Tom Dønnem, Sigurd Hald, Erna-Elise Paulsen, Elin Richardsen, Samer Al-Saad, Thomas Karsten Kilvær et al.:
    Stromal CD8+ T-cell density - A promising supplement to TNM staging in non-small cell lung cancer
    Clinical Cancer Research 2015 DOI
  • Sigurd Hald, Yury Kiselev, Samer Al-Saad, Elin Richardsen, Charles Johannessen, Marte Eilertsen et al.:
    Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: Combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival
    BMC Cancer 2015 ARKIV / DOI
  • Thomas Karsten Kilvær, Eivind Smeland, Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Roy M. Bremnes, Lill-Tove Busund et al.:
    The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk
    BMC Clinical Pathology 20. January 2014 FULLTEKST / ARKIV / DOI
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Al-Shibli et al.:
    Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas
    BMC Clinical Pathology 15. March 2013 FULLTEKST / ARKIV / DOI
  • Eivind Smeland, Thomas Karsten Kilvær, Sveinung Wergeland Sørbye, Andrey Yurjevich Valkov, Sigve Andersen, Roy M. Bremnes et al.:
    Prognostic Impacts of Hypoxic Markers in Soft Tissue Sarcoma
    Sarcoma 2012 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Ibrahim Al-Shibli et al.:
    Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas
    BMC Clinical Pathology 29. February 2012 FULLTEKST / ARKIV / DOI
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Ibrahim Al-Shibli et al.:
    Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas
    BMC Clinical Pathology 03. May 2012 FULLTEKST / ARKIV / DOI
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Al-Shibli et al.:
    Prognostic Impact of Jab1, p16, p21, p62, Ki67 and Skp2 in Soft Tissue Sarcomas
    PLOS ONE 2012 FULLTEKST / ARKIV / DOI
  • Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Tom Dønnem, Eivind Smeland, Roy M. Bremnes et al.:
    Estrogen receptor and progesterone receptor are prognostic factors in soft tissue sarcomas
    International Journal of Oncology 2011 DOI
  • Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Tom Dønnem, Eivind Smeland, Roy M. Bremnes et al.:
    The Prognostic Impact of TGF-beta 1, Fascin, NF-kappa B and PKC-zeta Expression in Soft Tissue Sarcomas
    PLOS ONE 2011 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Ibrahim Al-Shibli et al.:
    Prognostic Impact of Lymphocytes in Soft Tissue Sarcomas
    PLOS ONE 2011 ARKIV / DOI
  • Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Eivind Smeland, Roy M. Bremnes, Lill-Tove Busund et al.:
    Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients
    Journal of Translational Medicine 2011 ARKIV / DOI
  • Andrey Yurjevich Valkov, Thomas Karsten Kilvær, Sveinung Wergeland Sørbye, Tom Dønnem, Eivind Smeland, Roy M. Bremnes et al.:
    The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
    Journal of Translational Medicine 2011 ARKIV / DOI
  • Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Eivind Smeland, Roy M. Bremnes, Lill-Tove Rasmussen Busund et al.:
    Profiling of VEGFs and VEGFRs as prognostic factors in soft tissue sarcoma: VEGFR-3 is an independent predictor of poor prognosis
    PLOS ONE 14. December 2010 ARKIV / DOI
  • Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Sveinung Wergeland Sørbye, Tom Dønnem, Eivind Smeland, Roy M. Bremnes et al.:
    Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival
    Sarcoma 2010 DOI
  • Heidi Holmen, Are Martin Holm, Thomas Karsten Kilvær, Tone Marte Ljoså, Lars-Petter Ness Granan, Christopher Ekholdt et al.:
    Digital Outpatient Services for Adults: Development of an Intervention and Protocol for a Multicenter Non-Randomized Controlled Trial
    JMIR Research Protocols 2023 ARKIV / DOI
  • Heidi Holmen, Anna Hurrød, Christopher Ekholdt, Are Martin Holm, Thomas Karsten Kilvær, Lotte Sandberg Larsen et al.:
    Digital outpatient services: development of an intervention and a multicenter controlled trial
    2022
  • Heidi Holmen, Anna Hurrød, Christopher Ekholdt, Are Martin Holm, Saida Alfrida Martinez Overgaard, Lotte Sandberg Larsen et al.:
    Digital poliklinikk - utvikling av en intervensjon og en multisenterstudie
    2022
  • Kaja Konstanse Skjefstad, Thea K.W. Grindstad, Mehrdad Rakaee, Elin Richardsen, Tom Dønnem, Thomas Karsten Kilvær et al.:
    Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]
    Steroids 2018 DOI
  • Sigurd Hald, Yury Kiselev, Samer Al-Saad, Elin Helmine Richardsen, Charles Walquist Johannessen, Marte Eilertsen et al.:
    Erratum: Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: Combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. [BMC Cancer. 15, (2015) (441)] DOI: 10.1186/s12885-015-1446-z
    BMC Cancer 2016 DOI
  • Yury Kiselev, Andrey Yurjevich Valkov, Lill-Tove Busund, Roy M. Bremnes, Igor Snapkov, Ingvild Mikkola et al.:
    Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival
    2014
  • Sveinung Wergeland Sørbye, Thomas Karsten Kilvær, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Ibrahim Al-Shibli et al.:
    High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator
    Oncoimmunology 2012 ARKIV / DOI

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