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Forskningsgruppe for nukleærmedisin og strålebiologi emmet.mccormack@uit.no Tromsø

Mccormack, Emmet Matin



  • Katrin Kleinmanns, Stein-Erik Gullaksen, Geir Bredholt, Ben Davidson, Cecilie Fredvik Torkildsen, Sindre Grindheim et al.:
    Humanized Ovarian Cancer Patient-Derived Xenografts for Improved Preclinical Evaluation of Immunotherapies
    Cancers 2022 ARKIV / DOI
  • Vibeke Samuelsen Fosse, Emanuela Oldoni, Chiara Gerardi, Rita Banzi, Maddalena Fratelli, Florence Bietrix et al.:
    Evaluating Translational Methods for Personalized Medicine—A Scoping Review
    Journal of Personalized Medicine 19. July 2022 DOI
  • Spiros Kotopoulis, Mihaela-Lucia Popa, Mireia Mayoral Safont, Elsa Thodesen Murvold, Ragnhild Haugse, Anika Langer et al.:
    SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
    Pharmaceutics 2022 DOI
  • Spiros Kotopoulis, Christina Lam, Ragnhild Haugse, Sofie Snipstad, Elsa Thodesen Murvold, Tæraneh Jouleh et al.:
    Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery
    Ultrasonics sonochemistry 2022 ARKIV / DOI
  • Elvira García de Jalón , Katrin Kleinmanns, Vibeke Samuelsen Fosse, Ben Davidson, Line Bjørge, Bengt Erik Haug et al.:
    Comparison of Five Near-Infrared Fluorescent Folate Conjugates in an Ovarian Cancer Model
    Molecular Imaging and Biology 2021 ARKIV / DOI
  • Gorka Ruiz de Garibay, Elvira García de Jalón , Endre Stigen, Kjetil B. Lund, Mihaela-Lucia Popa, Ben Davidson et al.:
    Repurposing 18F-FMISO as a PET tracer for translational imaging of nitroreductase-based gene directed enzyme prodrug therapy
    Theranostics 2021 ARKIV / DOI
  • Juan Zhang, Graciela Terán, Mihaela-Lucia Popa, Harsha Madapura, Marcus J.G.W. Ladds, Danai Lianoudaki et al.:
    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
    iScience 2021 DOI
  • Ingvild Haaland, Sigrun Margrethe Hjelle, Håkon Reikvam, André Sulen, Anita Ryningen, Emmet Mc Cormack et al.:
    p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy
    Cells 2021 ARKIV / DOI
  • Øystein Solberg Eikrem, Spiros Kotopoulis, Mihaela-Lucia Popa, Mireia Mayoral Safont, Kjell Ove Fossan, Sabine Leh et al.:
    Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys
    Pharmaceutics 2021 DOI
  • Shamundeeswari Anandan, Liv Cecilie Vestrheim Thomsen, Stein-Erik Gullaksen, Tamim Abdelaal, Katrin Kleinmanns, Jørn Skavland et al.:
    Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods
    Cancers 2021 DOI
  • Christopher W. Schultz, Gorka Ruiz de Garibay, Anika Langer, Ji-Bin Liu, Teena Dhir, Calum Leitch et al.:
    Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model
    Cancer Biology & Therapy 2021 DOI
  • Elvira García de Jalón , Gorka Ruiz de Garibay, Bengt Erik Haug, Emmet Matin Mccormack :
    CytoCy5S™, a compound of many structures. in vitro and in vivo evaluation of four near-infrared fluorescent substrates of nitroreductase (NTR)
    Dyes and pigments 2021 DOI
  • Katrin Kleinmanns, Katharina Bischof, Shamundeeswari Anandan, Mihaela Lucia Popa, Lars A. Akslen, Vibeke Samuelsen Fosse et al.:
    CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
    EBioMedicine 2020 DOI
  • Ragnhild Haugse, Anika Langer, Elisa Thodesen Murvold, Daniela Elena Costea, Bjørn Tore Gjertsen, Odd Helge Gilja et al.:
    Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells
    Pharmaceutics 2020 DOI
  • Katrin Kleinmanns, Vibeke Samuelsen Fosse, Line Bjørge, Emmet McCormack :
    The emerging role of cd24 in cancer theranostics—a novel target for fluorescence image-guided surgery in ovarian cancer and beyond
    Journal of Personalized Medicine 27. November 2020 DOI
  • Katrin Kleinmanns, Vibeke Samuelsen Fosse, Ben Davidson, Elvira García de Jalón, Olav Tenstad, Line Bjørge et al.:
    CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model
    EBioMedicine 23. May 2020 ARKIV / DOI
  • Tina Fonnes, Elin Strand, Kristine Eldevik Fasmer, Hege Fredriksen Berg, Heidi Espedal, Kristina Sortland et al.:
    Near-Infrared Fluorescent Imaging for Monitoring of Treatment Response in Endometrial Carcinoma Patient-Derived Xenograft Models
    Cancers 2020 ARKIV / DOI
  • Tormod Karlsen Bjånes, Spiros Kotopoulis, Elsa Thodesen Murvold, Tina Kamceva, Bjørn Tore Gjertsen, Odd Helge Gilja et al.:
    Ultrasound‐ and microbubble‐assisted gemcitabine delivery to pancreatic cancer cells
    Pharmaceutics 2020 DOI
  • Gregory Lazarian, Chloe Friedrich, Anne Quinquenel, Julie Tran, Souhail Ouriemmi, Elisabeth Dondi et al.:
    Stabilization of β-catenin upon B-cell receptor signaling promotes NF-kB target genes transcription in mantle cell lymphoma
    Oncogene 2020 DOI
  • Elise Aasebø, Frode Berven, Sushma Bartaula-Brevik, Tomasz Stokowy, Randi Hovland, Marc Vaudel et al.:
    Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
    Cancers 2020 FULLTEKST / DOI
  • Maria Omsland, Vibeke Andresen, Stein-Erik Gullaksen, Maria del Pilar Ayuda-Duran, Mihaela Lucia Popa, Randi Hovland et al.:
    Tyrosine kinase inhibitors and interferon‐α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines (
    The FASEB Journal 2020 DOI
  • Tormod Karlsen Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer et al.:
    Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines
    Drug Metabolism And Disposition 2020 DOI
  • Rakel Brendsdal Forthun, Monica Hellesøy, Andre Sulen, Reidun Kristin Kopperud, Gry Sjøholt, Øystein Bruserud et al.:
    Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia
    Journal of Cancer Research and Clinical Oncology 2019 ARKIV / DOI
  • Elise Aasebø, Frode Berven, Sushma Bartaula-Brevik, Tomasz Stokowy, Randi Hovland, Marc Vaudel et al.:
    Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia
    bioRxiv - the preprint server for biology 2019 DOI
  • Ragnhild Haugse, Anika Langer, Stein-Erik Gullaksen, Silje Maria Sundøy, Bjørn Tore Gjertsen, Spiros Kotopoulis et al.:
    Intracellular signaling in key pathways is induced by treatment with ultrasound and microbubbles in a leukemia cell line, but not in healthy peripheral blood mononuclear cells
    Pharmaceutics 2019 ARKIV / DOI
  • Robert Hanes, Else Munthe, Iwona Grad, Jianhua Han, Ida Tveit Karlsen, Emmet Mc Cormack et al.:
    Preclinical Evaluation of the Pan-FGFR Inhibitor LY2874455 in FRS2-Amplified Liposarcoma
    Cells 2019 ARKIV / DOI
  • Gorka Ruiz de Garibay, Francesca Mateo, Agostina Stradella, Rafael Valdés-Mas, Luis Palomero, Jordi Serra-Musach et al.:
    Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance
    Disease Models and Mechanisms 2018 DOI
  • Marcus J.G.W. Ladds, Ingeborg M.M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova et al.:
    A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
    Nature Communications 2018 DOI
  • Katharina Bischof, Stian Knappskog, Ingunn Stefansson, Emmet McCormack, Jone Trovik, Henrica Maria Johanna Werner et al.:
    High expression of the p53 isoform ? is associated with reduced progression-free survival in uterine serous carcinoma
    BMC Cancer 2018 DOI
  • Marcus J.G.W. Ladds, Andrés Pastor-Fernández, Gergana Popova, Ingeborg M.M. van Leeuwen, Kai Er Eng, Catherine J. Drummond et al.:
    Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib
    PLOS ONE 2018 DOI
  • Spiros Kotopoulis, Endre Stigen, Mihaela Lucia Popa, Mireia Mayoral Safont, Andrew Healey, Svein Kvåle et al.:
    Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma
    Journal of Controlled Release 2017 DOI
  • Mihaela-Lucia Popa, Vibeke Samuelsen Fosse, Katrin Kleinmanns, Line Bjørge, Emmet McCormack :
    Xenograft Models of Ovarian Cancer for Therapy Evaluation
    Springer Nature 2021 DOI
  • Sahba Shafiee, Pascal Francois Gelebart, Mihaela-Lucia Popa, Monica Hellesøy, Randi Hovland, Rakel Brendsdal Forthun et al.:
    Preclinical characterisation and development of a novel myelodysplastic syndrome-derived cell line
    British Journal of Haematology 2021 DOI
  • Tormod Karlsen Bjånes, Bettina Riedel, Emmet McCormack, Jan Schjøtt :
    Drug delivery in pancreatic cancer
    2020
  • Tormod Karlsen Bjånes, Jan Schjøtt, Spiros Kotopoulis, Emmet McCormack, Bettina Riedel :
    Sonoporation and gemcitabine delivery in pancreatic cancer cell lines
    2019
  • Sahba Shafiee, Emmet McCormack :
    Translational Development of Preclinical Models and Therapies in Myelodysplastic Syndrome (MDS)
    2019 OMTALE
  • Elisa Ulvøen Thodesen, Tormod Karlsen Bjånes, Ragnhild Haugse, Odd Helge Gilja, Spiros Kotopoulis, Emmet McCormack :
    in vitro optimisation of sonoporation conditions in pancreatic cancer
    2019 FULLTEKST
  • Tormod Karlsen Bjånes, Elisa Ulvøen Thodesen, Jan Schjøtt, Spiros Kotopoulis, Bettina Riedel, Emmet McCormack :
    Sonoporation and gemcitabine delivery in pancreatic cell lines
    2019 FULLTEKST
  • Ragnhild Haugse, Anika Langer, Silje Maria Sundøy, Spiros Kotopoulis, Emmet McCormack :
    Molecular mechanisms of sonoporation in pancreatic ductal adenocarcinoma (PDAC)
    2019 FULLTEKST
  • Tormod Karlsen Bjånes, Lars Petter Jordheim, Jan Schjøtt, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis et al.:
    role of intracellular cytidine deaminase activity for gemcitabine metabolism in pancreatic cancer cell lines
    2019 FULLTEKST
  • Katrin Kleinmanns, Vibeke Samuelsen Fosse, Ben Davidson, Line Bjørge, Emmet McCormack :
    EP889 improved cytoreduction of ovarian cancer using CD24 targeted fluorescence image guided surgery in a preclinical murine model
    2019 FULLTEKST
  • Katharina Bischof, Line Bjørge, Bjørn Tore Gjertsen, Stian Knappskog, Emmet McCormack :
    Rethinking Gynecological High- Grade Serous Carcinoma. Portraying the p53 isoform landscape and development of a new preclinical for optical imaging in xenograft models
    2019 OMTALE
  • Beibei Zhang, Maria del Pilar Ayuda-Duran, Laure Isabelle Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont, Ida Tveit Karlsen et al.:
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica 2019 DOI
  • Tormod Karlsen Bjånes, Jan Schjøtt, Spiros Kotopoulis, Emmet McCormack, Bettina Riedel :
    Sonoporation and gemcitabine delivery in pancreatic cancer cell lines
    2019
  • Tormod Karlsen Bjånes, Lars Petter Jordheim, Jan Schjøtt, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis et al.:
    Intracellular cytidine deaminase and gemcitabine metabolism in three pancreatic cancer cell lines
    2019
  • Tormod Karlsen Bjånes, Lars Petter Jordheim, Jan Schjøtt, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis et al.:
    Intracellular cytidine deaminase and gemcitabine metabolism in three pancreatic cancer cell lines
    2019
  • Marcus J.G.W. Ladds, Ingeborg M.M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova et al.:
    Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
    Nature Communications 2018 DOI
  • May Eriksen Gjerstad, Emmet McCormack, Pascal Gelebart :
    Preclinical development of novel therapeutics in mantle cell lymphoma
    2018
  • Silje Maria Sundøy, Emmet McCormack, Ragnhild Haugse :
    Investigation of protein signalling pathways activated by sonoporation in cancer
    2018
  • Ida Tveit Karlsen, Emmet McCormack, Pascal Gelebart :
    Exploration of novel therapeutic options in mantle cell lymphoma
    2017

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