Arnfinn Ståle Sundsfjord


Professor of Clinical Microbiology


  • Hege Harboe-Sjåvik, Kristoffer Hammer Endresen, Sandra Elena Åsheim, Arnfinn Ståle Sundsfjord :
    FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2024 DOI
  • Aasmund Fostervold, Niclas Peter Raffelsberger, Marit Hetland, Ragna-Johanne Bakksjø, Eva Bernhoff, Ørjan Samuelsen et al.:
    Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages.
    Journal of Infection 2024 DOI
  • Paul Christoffer Lindemann, Torunn Pedersen, Dorthea Hagen Oma, Jessin Janice, Fredrik Grøvan, Ghantous Milad Chedid et al.:
    Intraregional hospital outbreak of OXA-244-producing Escherichia coli ST38 in Norway, 2020
    Eurosurveillance 2023 ARKIV / DOI
  • Theresa Wagner, Jessin Janice, Marc Schluz, Susan Ballard, Anders da Silva, Geoffrey W Coombs et al.:
    Reversible vancomycin susceptibility within emerging ST1421 Enterococcus faecium strains is associated with rearranged vanA-gene clusters and increased vanA plasmid copy number
    International Journal of Antimicrobial Agents 2023 ARKIV / DOI
  • Theresa Wagner, Benjamin P Howden, Arnfinn Sundsfjord, Kristin Hegstad :
    Transiently silent acquired antimicrobial resistance: an emerging challenge in susceptibility testing
    Journal of Antimicrobial Chemotherapy 2023 ARKIV / DOI
  • Marit Hetland, Jane Hawkey, Eva Bernhoff, Ragna-Johanne Bakksjø, Håkon Kaspersen, Siren Rettedal et al.:
    Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
    Microbial Genomics 2023 ARKIV / DOI
  • Kristin Hegstad, Anna Kaarina Pöntinen, Jørgen Bjørnholt, Else Quist Paulsen, Arnfinn Ståle Sundsfjord :
    The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure
    Journal of Global Antimicrobial Resistance 2023 ARKIV / DOI
  • Mushtaq Talib Shawi al Rubaye, Jessin Janice, Jørgen Bjørnholt, Iren Høyland Löhr, Arnfinn Ståle Sundsfjord, Kristin Hegstad :
    The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway – phenotypic and molecular characteristics
    Journal of Global Antimicrobial Resistance 2023 ARKIV / DOI
  • Mushtaq al Rubaye, Jessin Janice, Jørgen Vildershøj Bjørnholt, Oliver Kacelnik, Bjørg C. Haldorsen, Randi M. Nygaard et al.:
    The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by circulating global hospital-associated clones
    Microbial Genomics 2023 ARKIV / FULLTEKST / DOI
  • Niclas Peter Raffelsberger, Dorota Julia Buczek, Kristian Svendsen, Lars Småbrekke, Anna Kaarina Pöntinen, Iren Høyland Löhr et al.:
    Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates
    mSphere 2023 ARKIV / DOI
  • Oskar Ljungquist, Bjørg Haldorsen, Anna Kaarina Pöntinen, Jessin Janice, Ellen Haldis Josefsen, Petter Elstrøm et al.:
    Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021
    Eurosurveillance 06. July 2023 FULLTEKST / ARKIV / DOI
  • Tore Taksdal Stubhaug, Christian G. Giske, Ulrik S Justesen, Gunnar Kahlmeter, Erika Matuschek, Arnfinn Sundsfjord et al.:
    Antimicrobial susceptibility testing of Bacteroides species by disk diffusion: The NordicAST Bacteroides study
    Anaerobe 2023 ARKIV / DOI
  • Kirsten Midttun Gravningen, Oliver Kacelnik, Egil Lingaas, Torunn Pedersen, Bjørn Gunnar Iversen, Anne Mette Asfeldt et al.:
    Pseudomonas aeruginosa countrywide outbreak in hospitals linked to pre-moistened non-sterile washcloths, Norway, October 2021 to April 2022
    Eurosurveillance 2022 ARKIV / DOI
  • Kenneth Lindstedt, Dorota Julia Buczek, Torunn Annie Pedersen, Erik Hjerde, Niclas Peter Raffelsberger, Yutaka Suzuki et al.:
    Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods
    Gut microbes 31. August 2022 ARKIV / DOI
  • Faheema Ebrahim Choonara, Bjørg Haldorsen, Jessin Janice, Joshua Mbanga, Isaac Ndhlovu, Osborne Saulosi et al.:
    Molecular Epidemiological Characterisation of ESBL- and Plasmid-Mediated AmpC-Producing Escherichia coli and Klebsiella pneumoniae at Kamuzu Central Hospital, Lilongwe, Malawi
    Tropical Medicine and Infectious Disease 2022 ARKIV / DOI
  • Faheema E. Choonara, Bjørg Haldorsen, Isaac Ndhlovu, Osborne Saulosi, Tarsizio Maida, Fanuel Lampiao et al.:
    Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi
    Malawi Medical Journal 2022 ARKIV / DOI
  • Caillan Crowe-McAuliffe, Victoriia Murina, Kathryn Jane Turnbull, Susanne Huch, Marje Kasari, Hiraku Takada et al.:
    Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics
    Nature Communications 2022 ARKIV / DOI
  • Mushtaq T.S. Al-Rubaye, Jessin Janice, Jørgen Vildershøj Bjørnholt, Aleksandra Jakovljev, Maria Elisabeth Hultström, Arnfinn Sundsfjord et al.:
    Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
    PLOS ONE 2021 ARKIV / DOI
  • Jessin Janice, Nicholas Agyepong, Alex Owusu-Ofori, Usha Govinden, Sabiha Essack, Ørjan Samuelsen et al.:
    Carbapenem resistance determinants acquired through novel chromosomal integrations in extensively drug-resistant pseudomonas aeruginosa
    Antimicrobial Agents and Chemotherapy 2021 ARKIV / DOI
  • Niclas Peter Raffelsberger, Marit Andrea Klokkhammer Hetland, Kristian Svendsen, Lars Småbrekke, Iren Høyland Löhr, Lotte Andreassen et al.:
    Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity
    Gut microbes 2021 ARKIV / DOI
  • Marit Østlyngen Riibe, Sveinung Wergeland Sørbye, Gunnar Skov Simonsen, Arnfinn Sundsfjord, Josef Ekgren, Jan Martin Maltau :
    Risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) among women with HPV-test in 1990–1992, a 30-year follow-up study
    Infectious Agents and Cancer 2021 ARKIV / DOI
  • Abel F.N.D. Phiri, Akebe Luther King Abia, Daniel Gyamfi Amoako, Rajab Mkakosya, Arnfinn Sundsfjord, Sabiha Essack et al.:
    Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi
    Tropical Medicine and Infectious Disease 2021 ARKIV / DOI
  • Aasmund Fostervold, Marit Andrea Klokkhammer Hetland, Ragna-Johanne Bakksjø, Eva Bernhoff, Kathryn E. Holt, Ørjan Samuelsen et al.:
    A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001–15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307
    Journal of Antimicrobial Chemotherapy 2021 ARKIV / DOI
  • Calvina Estalva, Tomas Zimba, Sekyere John, Usha Govinden, Hafizah Y. Chenia, Gunnar Skov Simonsen et al.:
    High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
    BMC Infectious Diseases 2021 ARKIV / DOI
  • Fredrik Håkonsholm, Marit Andrea Klokkhammer Hetland, Cecilie Smith Svanevik, Arnfinn Sundsfjord, Bjørn Tore Lunestad, Nachiket Marathe :
    Antibiotic sensitivity screening of Klebsiella spp. and Raoultella spp. isolated from marine bivalve molluscs reveal presence of CTX-M-producing K. pneumoniae
    Microorganisms 30. November 2020 ARKIV / DOI
  • Theresa Wagner, Jessin Janice, Audun Sivertsen, Ingegerd Sjögren, Arnfinn Sundsfjord, Kristin Hegstad :
    Alternative vanHAX promoters and increased vanA-plasmid copy number resurrect silenced glycopeptide resistance in Enterococcus faecium
    Journal of Antimicrobial Chemotherapy 2020 ARKIV / DOI
  • Sara Lino Faife, Tomas Zimba, John Osei Sekyere, Usha Govinden, Hafizah Y. Chenia, Gunnar Skov Simonsen et al.:
    β-lactam and fluoroquinolone resistance in Enterobacteriaceae from imported and locally-produced chicken in Mozambique
    Journal of Infection in Developing Countries 2020 ARKIV / DOI
  • Veronika Vorobieva, Anne-Sofie Furberg, Hans-Christian Slotved, Tatiana Bazhukova, Bjørg Haldorsen, Dominique A Caugant et al.:
    Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines
    BMC Infectious Diseases 2020 FULLTEKST / ARKIV / DOI
  • Alison Holmes, Mark Holmes, Thomas Gottlieb, Lance B Price, Arnfinn Sundsfjord :
    End non-essential use of antimicrobials in livestock
    The BMJ 2019 DOI
  • Nicholas Agyepong, Usha Govinden, Alex Owusu-Ofori, Daniel Gyamfi Amoako, Mushal Allam, Jessin Janice James Peter et al.:
    Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital
    International Journal of Infectious Diseases 2019 ARKIV / DOI
  • Ilya Nikolaevich Zykov, Niels Frimodt-Møller, Lars Småbrekke, Arnfinn Sundsfjord, Ørjan Samuelsen :
    Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model
    International Journal of Antimicrobial Agents 02. November 2019 ARKIV / DOI
  • Torunn Annie Pedersen, John Osei Sekyere, Usha Govinden, Krishnee Moodley, Audun Sivertsen, Ørjan Samuelsen et al.:
    Spread of plasmid-encoded NDM-1 and GES-5 carbapenemases among extensively drug-resistant and pandrug-resistant clinical enterobacteriaceae in durban, South Africa
    Antimicrobial Agents and Chemotherapy 2018 DOI
  • Marit Hetland, Mia Angelique Winkler, Thomas D Stanton, Ryan R. Wick, Margaret MC Lam, Aasmund Fostervold et al.:
    Klebsiella pneumoniae ecology and antimicrobial resistance in a One Health perspective
    2023
  • Fredrik Håkonsholm, Arnfinn Sundsfjord, Cecilie Smith Svanevik, Bjørn Tore Lunestad, Nachiket Marathe :
    Klebsiella pneumoniae in the marine setting – a challenge for seafood safety?
    2023
  • Morten Lindbæk, Arnfinn Ståle Sundsfjord :
    Improving antibiotic prescribing for uncomplicated UTIs
    The BMJ 2023 DOI
  • Theresa Maria Wagner, Anna Kaarina Pöntinen, Mushtaq T.S. AL Rubaye, Arnfinn Ståle Sundsfjord, Kristin Hegstad :
    Adaptive cell wall thickening in Enterococcus faecalis is associated with decreased vancomycin susceptibility
    Clinical Microbiology and Infection (CMI) 2023 DOI
  • Klara Stensvåg, Arnfinn Sundsfjord, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Lise Nordgård :
    CANS - Centre for New Antibacterial Strategies
    2022 PROSJEKT
  • Marit Hetland, Jane Hawkey, Eva Bernhoff, Ragna-Johanne Bakksjø, Håkon Kaspersen, Siren Rettedal et al.:
    Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
    2022
  • Yngvild Wasteson, Henning Sørum, Bjørn-Arne Lindstedt, Arnfinn Sundsfjord, Hans Geir Eiken, Erik Joner et al.:
    CORNELIA – Antimicrobial Resistance (AMR) in One Health Interfaces
    2021 PROSJEKT
  • Bjørg C Haldorsen, Erika Matuschek, Jenny Åhman, Gunnar Kahlmeter, Arnfinn Sundsfjord, Kristin Hegstad :
    Performance of the EUCAST disc diffusion method and gradient tests in detection of linezolid susceptibility in Enterococcus faecalis and Enterococcus faecium
    2021
  • Theresa Wagner, Jessin Janice James Peter, Marc Schulz, Susan A. Ballard, Anders Goncalves da Silva, Geoffrey W Coombs et al.:
    Australian vancomycin variable E. faecium ST1421 revert to resistance by the use of an alternative vanHAX promoter and increased vanA-plasmid copy number
    2021
  • Yngvild Wasteson, Henning Sørum, Bjørn-Arne Lindstedt, Adriana Dorota Osinska, Arnfinn Sundsfjord, Hans Geir Eiken et al.:
    CORNELIA – Antimicrobial Resistance (AMR) in One Health Interfaces
    2021
  • Paul Christoffer Lindemann, Karianne Wiger Gammelsrud, Iren Høyland Löhr, Per Espen Akselsen, Morten Lindbæk, Arnfinn Sundsfjord :
    Valg av antibiotika - viktig endring i prøvesvar fra mikrobiologen
    Tidsskrift for Den norske legeforening 2019 DOI
  • Nicholas Agyepong, Usha Govinden, Alex Owusu-Ofori, Mushal Allam, Arshad Ismail, Torunn Annie Pedersen et al.:
    Whole-genome sequences of two multidrug-resistant acinetobacter baumannii strains isolated from patients with urinary tract infection in Ghana
    Microbiology Resource Announcements (MRA) 2019 DOI
  • Theresa Wagner, Jessin Janice, Audun Sivertsen, Ingegerd Sjögren, Arnfinn Sundsfjord, Kristin Hegstad :
    The bag of tricks of vancomycin variable enterococci: an alternative constitutive vanHAX-promoter, varying copy numbers and transferable resistance
    2019
  • Mushtaq Talib Shawi Al-Rubaye, Jessin Janice, Iren Høyland Löhr, Arnfinn Sundsfjord, Kristin Hegstad :
    THE FIRST VANE VANCOMYCIN RESISTANT ENTEROCOCCUS FAECALIS IN NORWAY
    2019
  • Mushtaq Talib Shawi Al-Rubaye, Jessin Janice, Jørgen Vildershøj Bjørnholt, Oliver Kacelink, Biørg C. Haldorsen, Randi M. Nygaard et al.:
    POPULATION STRUCTURE OF THE NORWEGIAN VANCOMYCIN RESISTANT AND SENSITIVE ENTEROCOCCI 2010-2015
    2019
  • A Basic, Erika Matuschek, O Karatuna, Bjørg C Haldorsen, Kristin Hegstad, Jenny Åhman et al.:
    Evaluation of gradient tests for vancomycin MIC determination in Enterococcus faecalis and Enterococcus faecium. Effect of incubation for 16-20 hours vs. 24 hours
    2019
  • Lyn Middleton, F Lampiao, Tomas F. Zimba, SM Muzime, Gunnar Skov Simonsen, Lars Småbrekke et al.:
    Sharing Knowledge Transforming Societies. The Norhed Programme 2013-2020
    African Minds 2019
  • Jessin Janice James Peter, Joachim Hegstad, Ellen H. Josefsen, Arnfinn Sundsfjord, Kristin Hegstad :
    Increased prevalence of linezolid resistance mong clinical enterococci in Norway mainly due to spread of optrA E. faecalis
    2019

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    Research interests

    • Antimicrobials, antimicrobial resistance and evolution
    • Klebsiella pneumoniae (Kp) is a key player in the global spread of antimicrobial resistance (AMR). Our studies involve comparative molecular epidemiological studies (whole genome sequencing and metagenomics), pheno- and genotypic associations in pathogenicity and antimicrobial susceptibility (GWAS and machine learning), as well as preclinical effectstudies of bacteriophages in the containment of carriage of and infections caused by multidrug resistant Kp. Kp-studies are funded by the Trond Mohn Foundation ( https://mohnfoundation.no/amr-prosjekter/) and partner institutions.
    • Program director, Centre for New Antibacterial Strategies (CANS; https://uit.no/research/cans): En interdisiplinary research center funded by UiT and the Tromsø Research Foundation (https://tfstiftelse.no/) 2019-.
    • Medical Director, National Norwegian Advisory Unit in Detection of Antimicrobial Resistance (K-res; https://unn.no/fag-og-forskning/k-res) at the University Hospital of North-Norway (UNN) funded by the Norwegian Ministry of Health, the Northern Regional Health Authority, and UNN. 



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