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Associate Professor

Nymo, Stig Haugset

Department of Clinical Medicine
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  • Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik; Brekke, Ole-Lars. Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.. Clinical and Experimental Immunology 2018. ISSN 0009-9104.s doi: 10.1111/cei.13240.

  • Harboe, Morten; Johnson, Christina; Nymo, Stig Haugset; Ekholt, Karin; Schjalm, Camilla; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik; Nilsson, Per. Properdin binding to complement activating surfaces depends on initial C3b deposition. Proceedings of the National Academy of Sciences of the United States of America 2017; Volum 114 (4). ISSN 0027-8424.s E534 - E539.s doi: 10.1073/pnas.1612385114.

  • Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology 2016; Volum 196 (5). ISSN 0022-1767.s 2293 - 2299.s doi: 10.4049/jimmunol.1502220.

  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases 2016; Volum 214 (1). ISSN 0022-1899.s 140 - 150.s doi: 10.1093/infdis/jiw100.

  • Berg, Åse; Otterdal, Kari; Patel, Sam; Gonca, Miguel; David, Catarina; Dalen, Ingvild; Nymo, Stig Haugset; Nilsson, Margareta; Nordling, Sofia; Magnusson, Peetra U.; Ueland, Thor; Prato, Mauro; Giribaldi, Giuliana; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina; Nilsson, Per. Complement activation correlates with disease severity and contributes to cytokine responses in plasmodium falciparum malaria. Journal of Infectious Diseases 2015; Volum 212 (10). ISSN 0022-1899.s 1835 - 1840.s doi: 10.1093/infdis/jiv283.

  • Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna; Espevik, Terje; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik. The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology 2015; Volum 181 (3). ISSN 0009-9104.s 457 - 467.s doi: 10.1111/cei.12645.

  • Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology 2014; Volum 219 (10). ISSN 0171-2985.s 786 - 792.s doi: 10.1016/j.imbio.2014.06.006.

  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology 2014; Volum 192 (6). ISSN 0022-1767.s 2837 - 2845.s doi: 10.4049/jimmunol.1302484.

  • Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari; Nymo, Stig Haugset; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30 2015.

  • Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. Cholesterol crystals induce complement-dependent inflammasome activation. NBS Contact Meeting 2014-01-23 - 2014-01-25 2014.

  • Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv; Brekke, Ole Lars; Latz, E; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology 2013; Volum 56 (3). ISSN 0161-5890.s 246 - 246.s doi: 10.1016/j.molimm.2013.05.026.

  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars; Sandanger, I; Aukrust, Pål; Damås, Jan Kristian; Latz, Eicke; Lambris, J.D.; Mollnes, Tom Eirik; Espevik, Terje. Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology 2013; Volum 56 (3). ISSN 0161-5890.s 260 - 260.s doi: 10.1016/j.molimm.2013.05.061.

  • Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv; Brekke, Ole Lars; Lappegard, Knut Tore; Damas, Jan Kristian; Latz, Eicke; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology 2012; Volum 217 (11). ISSN 0171-2985.s 1157 - 1157.s doi: 10.1016/j.imbio.2012.08.079.

  • Nymo, Stig; Kuklin, Vladimir; Zykova, Svetlana; Bjertnaes, Lars J.. RECOMBINANT HUMAN ACTIVATED PROTEIN C HAS A GLOBAL MODULATING EFFECT ON THE INFLAMMATORY RESPONSE IN MURINE SEPSIS. Intensive Care Medicine 2010; Volum 36. ISSN 0342-4642.s S193 - S193.

  • Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari; Nymo, Stig Haugset; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30 2015.

  • Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. Cholesterol crystals induce complement-dependent inflammasome activation. NBS Contact Meeting 2014-01-23 - 2014-01-25 2014.

  • Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv; Brekke, Ole Lars; Latz, E; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology 2013; Volum 56 (3). ISSN 0161-5890.s 246 - 246.s doi: 10.1016/j.molimm.2013.05.026.

  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars; Sandanger, I; Aukrust, Pål; Damås, Jan Kristian; Latz, Eicke; Lambris, J.D.; Mollnes, Tom Eirik; Espevik, Terje. Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology 2013; Volum 56 (3). ISSN 0161-5890.s 260 - 260.s doi: 10.1016/j.molimm.2013.05.061.

  • Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv; Brekke, Ole Lars; Lappegard, Knut Tore; Damas, Jan Kristian; Latz, Eicke; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology 2012; Volum 217 (11). ISSN 0171-2985.s 1157 - 1157.s doi: 10.1016/j.imbio.2012.08.079.

  • Nymo, Stig; Kuklin, Vladimir; Zykova, Svetlana; Bjertnaes, Lars J.. RECOMBINANT HUMAN ACTIVATED PROTEIN C HAS A GLOBAL MODULATING EFFECT ON THE INFLAMMATORY RESPONSE IN MURINE SEPSIS. Intensive Care Medicine 2010; Volum 36. ISSN 0342-4642.s S193 - S193.

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