Bilde av Ahator, Stephen Dela
Bilde av Ahator, Stephen Dela
Researcher Department of Pharmacy stephen.d.ahator@uit.no Tromsø

Stephen Dela Ahator


Job description

Stephen Dela Ahator is a researcher in the Drug Transport and Delivery Research Group within the Department of Pharmacy. His work focuses on the development of liposomal nanoparticles for the targeted delivery of biologics including peptides, nucleic acids, and proteins, primarily for pulmonary administration and thrombotic cell targeting.

Stephen’s long-term research vision is to integrate his expertise in cell and molecular biology, drug development and delivery systems, and computational science to better understand the dynamics of infectious diseases and overcome barriers in targeted drug delivery. His goal is to contribute to the development of effective therapeutics for complex infections and diseases. He is passionate about advancing innovative strategies that bridge biology and technology to improve treatment outcomes and expand access to precision medicine.


  • Nana Eghele Adade, Stephen Dela Ahator, Inmaculada García-Romero, Macarena Algarañás, Vincent Appiah, Miguel A. Valvano et al.:
    Stress adaptation under in vitro evolution influences survival and metabolic phenotypes of clinical and environmental strains of Vibrio cholerae El-Tor
    Microbiology spectrum 2025 DOI
  • Stephen Dela Ahator, Kjersti Julin, Md Jalal Uddin, Christian Lentz :
    Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation
    Nature Communications 2025 DOI
  • Stephen Dela Ahator, Karoline Wenzl, Kristin Hegstad, Christian Stephan Lentz, Mona Susan Johannessen :
    Comprehensive virulence profiling and evolutionary analysis of specificity determinants in Staphylococcus aureus two-component systems
    mSystems 2024 DOI / ARKIV
  • Stephen Dela Ahator, Kristin Hegstad, Christian Stephan Lentz, Mona Susan Johannessen :
    Deciphering Staphylococcus aureus–host dynamics using dual activity-based protein profiling of ATP-interacting proteins
    mSystems 2024 DOI / ARKIV
  • Matthias Fellner, Annabel Walsh, Stephen Dela Ahator, Nadia Aftab, Ben Sutherland, Eng W Tan et al.:
    Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response
    ACS Infectious Diseases 2023 DOI / ARKIV
  • Nana Eghele Adade, Yaw Aniweh, Lydia Mosi, Miguel A. Valvano, Samuel Duodu, Stephen Dela Ahator :
    Comparative analysis of Vibrio cholerae isolates from Ghana reveals variations in genome architecture and adaptation of outbreak and environmental strains
    Frontiers in Microbiology 2022 DOI / ARKIV
  • Stephen Dela Ahator, Yang Liu, Jianhe Wang, Lian-Hui Zhang :
    The virulence factor regulator and quorum sensing regulate the type I-F CRISPR-Cas mediated horizontal gene transfer in Pseudomonas aeruginosa
    Frontiers in Microbiology 2022 DOI / ARKIV
  • Yang Liu, Stephen Dela Ahator, Huishan Wang, Qishun Feng, Yinuo Xu, Chuhao Li et al.:
    Microevolution of the mexT and lasR Reinforces the Bias of Quorum Sensing System in Laboratory Strains of Pseudomonas aeruginosa PAO1
    Frontiers in Microbiology 2022 DOI / ARKIV
  • Stephen Dela Ahator, Sadhanna Sagar, Minya Zhu, Jianhe Wang, Lian-Hui Zhang :
    Nutrient Availability and Phage Exposure Alter the Quorum-Sensing and CRISPR-Cas-Controlled Population Dynamics of Pseudomonas aeruginosa
    mSystems 2022 DOI / ARKIV
  • Stephen Dela Ahator :
    Harnessing the Power of ATP: Deciphering Host-Pathogen Dynamics in S. aureus Infections
    2023
  • Stephen Dela Ahator :
    Pint Sized Pathogens: Disrupting bacterial chatter to outsmart infections
    2023
  • Stephen Dela Ahator :
    Exploring the mysteries of S. aureus infections: unveiling host-pathogen interactions through ATP interactions
    2023

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    Research interests

     

    Drug Transport and Delivery Systems
    Focus on the design and optimization of advanced drug delivery platforms, including liposomal nanoparticles and targeted carriers, to enhance the bioavailability and therapeutic efficacy of biologicals
    Computational Biology and Omics Integration
    I apply computational tools and systems biology approaches to integrate multi-omics data (genomics, transcriptomics, chemo/proteomics, and metagenomics) for a holistic understanding of disease mechanisms.
    Microbial Genetics, Sociomicrobiology, and Evolution
    Keen on investigating microbial behaviour, genetic adaptation, and community interactions, with a focus on antibiotic resistance, quorum sensing, and biofilm formation.



    Member of project