Bilde av Skalko-Basnet, Natasa
Photo: Bjørn-Kåre Iversen
Bilde av Skalko-Basnet, Natasa
Research Group leader Department of Pharmacy natasa.skalko-basnet@uit.no +4777646640 You can find me here

Natasa Skalko-Basnet


Job description

Professor and Head of Drug Transport and Delivery Research Group

Responsible for courses in Pharmaceutics and Biopharmaceutics:

FAR 3041 Advanced Pharmaceutics and Biopharmaceutics

FAR 3043 Advanced Drug Delivery Systems in Nanomedicine (Master course)

FAR 8043 Nanotechnology and Nanomedicine (PhD course)


  • Sathi Das, Jean-Claude Tinguely, Sybil Akua Okyerewa Obuobi, Natasa Skalko Basnet, Kanchan Saxena, Balpreet Singh Ahluwalia et al.:
    Plasmonic nano-bowls for monitoring intra-membrane changes in liposomes, and DNA-based nanocarriers in suspension
    Biomedical Optics Express 2024 ARKIV / DOI
  • Silje Mork, Mona Susan Johannessen, Natasa Skalko Basnet, May Wenche Bakke Jøraholmen :
    Chitosan and liposomal delivery systems for epicatechin or propyl gallate targeting localized treatment of vulvovaginal candidiasis
    International Journal of Pharmaceutics 2024 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Virginia Panzacchi, Lloyd Mbugua Kangu, Barbara Giordani, Barbara Luppi, Natasa Skalko-Basnet :
    Lecithin and Chitosan as Building Blocks in Anti-Candida Clotrimazole Nanoparticles
    Pharmaceuticals 2023 ARKIV / DOI
  • Ana Cacic, Daniela Amidžic Klaric, Sabina Keser, Maja Radikovic, Zora Rukavina, May Wenche Jøraholmen et al.:
    A Novel Approach for the Treatment of Aerobic Vaginitis: Azithromycin Liposomes-in-Chitosan Hydrogel
    Pharmaceutics 2023 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Barbara Giordani, Marianne Hagensen Paulsen, Zeljka Vanic, Gøril Eide Flaten, Beatrice Vitali et al.:
    Tailored anti-biofilm activity – Liposomal delivery for mimic of small antimicrobial peptide
    Biomaterials Advances 2023 ARKIV / DOI
  • Alexandra Sofia Antunes de Sousa, Anna Ngoc Phung, Natasa Skalko-Basnet, Sybil Akua Okyerewa Obuobi :
    Smart delivery systems for microbial biofilm therapy: Dissecting design, drug release and toxicological features
    Journal of Controlled Release 2023 ARKIV / DOI
  • Alexandra Sofia Antunes de Sousa, Vegard Borøy, Agnethe Hansen Bæverud, Kjersti Julin, Annette Bayer, Morten B. Strøm et al.:
    Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa
    Journal of materials chemistry. B 2023 ARKIV / DOI
  • Zora Rukavina, May Wenche Bakke Jøraholmen, Dunja Mercury Božić, Ivana Frankol, Petra Golja Gasparovic, Natasa Skalko Basnet et al.:
    Azithromycin-loaded liposomal hydrogel: a step forward for enhanced treatment of MRSA-related skin infections
    Acta Pharmaceutica 2023 DOI
  • Miriam Soledad Giambelluca, Elena Markova, Claire Louet, Bjørg Steinkjer, Rune Sundset, Natasa Skalko Basnet et al.:
    Liposomes - Human phagocytes interplay in whole blood: effect of liposome design
    Nanomedicine: Nanotechnology, Biology and Medicine 2023 ARKIV / DOI
  • Ann Mari Holsæter, Kristina Wizgird, Iselin Karlsen, Jeanette Frimand Hemmingsen, Martin Brandl, Natasa Skalko-Basnet :
    How docetaxel entrapment, vesicle size, zeta potential and stability change with liposome composition–A formulation screening study
    European Journal of Pharmaceutical Sciences 2022 ARKIV / DOI
  • Nikhil Jayakumar, Firehun Tsige Dullo, Vishesh Kumar Dubey, Azeem Ahmad, Florian Ströhl, Jennifer Cauzzo et al.:
    Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy
    Nanophotonics 2022 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Pimmat Panchai, Kjersti Julin, Purusotam Basnet, Mona Nystad, Mona Johannessen et al.:
    Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine
    Frontiers in Microbiology 2022 ARKIV / DOI
  • Eirik André Lindeløff Rustad, Susannah von Hofsten, Robin Kumar, Eirik Abrahamsen Lænsman, Gerd Berge, Natasa Skalko-Basnet :
    The pH-Responsive Liposomes—The Effect of PEGylation on Release Kinetics and Cellular Uptake in Glioblastoma Cells
    Pharmaceutics 2022 ARKIV / DOI
  • May Wenche Jøraholmen, Pauliina Damdimopoulou, Ganesh Acharya, Natasa Skalko-Basnet :
    Toxicity Assessment of Resveratrol Liposomes-in-Hydrogel Delivery System by EpiVaginal™ Tissue Model
    Pharmaceutics 2022 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Kjersti Julin, Luquman Mian Ahsan, Purusotam Basnet, Mona Johannessen, Natasa Skalko-Basnet :
    Chitosomes-in-chitosan hydrogel for acute skin injuries: Prevention and infection control
    Marine Drugs 2021 ARKIV / DOI
  • Ivo Laidmae, Andres Meos, Irja Alainezhad Kjærvik, Sveinung Gaarden Ingebrigtsen, Natasa Skalko-Basnet, Kalle Kirsimäe et al.:
    Electrospun Amphiphilic Nanofibers as Templates for In Situ Preparation of Chloramphenicol-Loaded Liposomes
    Pharmaceutics 2021 ARKIV / DOI
  • Jostein Grip, Erik Steene, Rolf Einar Engstad, Jeff Hart, Andrea Bell, Ingrid Skjæveland et al.:
    Development of a novel beta-glucan supplemented hydrogel spray formulation and wound healing efficacy in a db/db diabetic mouse model
    European journal of pharmaceutics and biopharmaceutics 2021 ARKIV / DOI
  • Gøril Eide Flaten, Zeljka Vanic, Natasa Skalko-Basnet :
    The Role of In Vitro Skin Models in Optimization of Dermal Drug Delivery
    CRC Press 2021
  • May Wenche Jøraholmen, Selenia Ternullo, Ann Mari Holsæter, Gøril Eide Flaten, Natasa Skalko-Basnet :
    Advanced Drug Delivery Systems for Biologics
    John Wiley & Sons 2021
  • Marek Soltys, David Zuza, Tereza Boleslavska, Sarah Machac Akhlasova, Martin Balouch, Pavel Kovacik et al.:
    Drug loading to mesoporous silica carriers by solvent evaporation: A comparative study of amorphization capacity and release kinetics
    International Journal of Pharmaceutics 2021 ARKIV / DOI
  • Lisa Myrseth Hemmingsen, Natasa Skalko-Basnet, May Wenche Jøraholmen :
    The Expanded Role of Chitosan in Localized Antimicrobial Therapy
    Marine Drugs 2021 ARKIV / DOI
  • Elena Markova, Camilla Izabel Wolowczyk, Alexandros Marios Sofias, Sjoerd Hak, Natasa Skalko Basnet :
    Liposomal nor-NOHA: A Promising Strategy for Targeted Cancer Immunotherapy
    2024
  • Natasa Skalko Basnet :
    Academic research (in nanomedicine)
    2024
  • Ali Raza, Natasa Skalko Basnet, Sybil Akua Okyerewa Obuobi :
    Shape-memory hydrogel film for prolonged gastric retention to deliver antibiotic against H. pylori infection
    2024
  • Silje Mork, Natasa Skalko Basnet, May Wenche Bakke Jøraholmen :
    Utilizing chitosan-modified liposomal formulations as delivery systems for epicatechin in the localized treatment of vulvovaginal candidiasis
    2024
  • Dmytro Kravtsov, Mona Susan Johannessen, Mauri A Kostiainen, Natasa Skalko Basnet, Sybil Akua Okyerewa Obuobi :
    Rational design of aptamer-based nanostructures for bacterial biofilm applications
    2024
  • Natasa Skalko Basnet :
    Drug delivery: why, where and how
    2024
  • Alexandra Sofia Antunes De Sousa, Mona Susan Johannessen, Annette Bayer, Morten Bøhmer Strøm, Natasa Skalko Basnet, Sybil Akua Okyerewa Obuobi :
    Study of the penetration ability of DNA nanoparticles in biofilms
    2024
  • Maddhusja Sritharan Nalliah, Øystein Grimstad, Natasa Skalko Basnet, Lisa Myrseth Hemmingsen :
    Developing a topical nanoformulation for atopic dermatitis
    2024
  • Marta Mantegna, Natasa Skalko Basnet, Gøril Eide Flaten :
    The Colonic-PVPA: a new application for the mucus-comprising artificial in vitro permeability model
    2024
  • Velentza Paraskevi, Mats Rune Pettersen, Øystein Grimstad, Francesco Cilurzo, Natasa Skalko Basnet, Silvia Franzè et al.:
    Lipid nanoparticles to modulate gene delivery into dermal cells: the role of lipid and plasmid content on cellular uptake and transfection
    2024
  • Natasa Skalko Basnet :
    Efficient vaginal drug delivery: more important than ever
    2024
  • Alexandra Sofia Antunes de Sousa, Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet et al.:
    Drug-loaded DNA nanoparticles against bioflms
    2023
  • Natasa Skalko-Basnet :
    Why is drug delivery so important in drug development?
    2023
  • Lisa Myrseth Hemmingsen, Barbara Giordani, Marianne Hagensen Paulsen, Zeljka Vanic, Gøril Eide Flaten, Beatrice Vitali et al.:
    Liposomes in topical delivery of mimic of small antimicrobial peptide - Improving the anti-biofilm effect
    2023
  • Eirik André Lindeløff Rustad, Stine Figenschau, gerd Berge, Natasa Skalko Basnet :
    Role of liposomal PEGylation on protein corona formation and cellular uptake mechanisms
    2023
  • Jan Fredrik Frantzen, Natasa Skalko-Basnet, Gøril Eide Flaten :
    Kvinnelig rekrutteringssuksess med egen professor-filosofi
    08. March 2022
  • Lisa Myrseth Hemmingsen, Gøril Eide Flaten, Morten B. Strøm, Natasa Skalko-Basnet :
    Membrane-active antimicrobials – in synergy with nature – the role of chitosan
    2022
  • Lisa Myrseth Hemmingsen, Natasa Skalko-Basnet :
    Addressing skin wound biofilms in an era of antimicrobial resistance: the potential of membrane-active antimicrobials
    2022
  • Lisa Myrseth Hemmingsen, Barbara Giordani, Ann Kristin Pettersen, Beatrice Vitali, Purusotam Basnet, Natasa Skalko-Basnet :
    Synergy in action: Chitosan as anti-biofilm booster
    2022
  • Nikhil Jayakumar, Firehun Tsige Dullo, Vishesh Kumar Dubey, Azeem Ahmad, Florian Ströhl, Jennifer Cauzzo et al.:
    Erratum: Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy (Nanophotonics DOI: 10.1515/nanoph-2022-0500.pdf)
    Nanophotonics 2022 DOI
  • Silje Mork, Natasa Skalko-Basnet, May Wenche Jøraholmen :
    Chitosan-coated liposomes as delivery systems of polyphenols for topical administration
    2022
  • Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet, Sybil Akua Okyerewa Obuobi :
    DNA Nanocarriers for improved biofilm penetration
    2022
  • Laura Schulte Werning, Natasa Skalko-Basnet, Ann Mari Holsæter :
    Needle-free electrospinning of nanofibers with chloramphenicol-liposomes using the NanospiderTM
    2022
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Multi-responsive and Zwitterionic Nanohybrids for the Treatment of Biofilm Wound Infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Zwitterionic hybrid nanoparticles for the treatment of biofilm wound infections
    2021
  • Natasa Skalko-Basnet :
    Barriers to Vaginal Drug Delivery
    2021
  • Natasa Skalko-Basnet :
    Nanomedicine for localized therapy of genital infections: overcoming antimicrobial resistance
    2021
  • Nikhil Jayakumar, Firehun Tsige Dullo, Vishesh Kumar Dubey, Azeem Ahmad, Jennifer Cauzzo, Eduarda Mazagao Guerreiro et al.:
    Label-free imaging on waveguide platform with enhanced resolution and contrast
    2021 ARKIV
  • Eirik André Lindeløff Rustad, May Wenche Jøraholmen, Rune Sundset, Natasa Skalko-Basnet :
    pH-Responsive Liposomes Targeting Glioblastoma
    2021

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    Research interests

    dvanced drug delivery systems for localized therapy

    Advanced drug delivery systems for systemic therapy

    Lipid-based delivery systems

     Hydrogels

     

     

     

     

    Teaching

    Responsible for courses in Pharmaceutics and Biopharmaceutics:

    FAR 3041 Advanced Pharmaceutics and Biopharmaceutics

    FAR 3043 Advanced Drug Delivery Systems in Nanomedicine (Master course)

    FAR 8043 Nanotechnology and Nanomedicine (PhD course)




    CV

    CURRICULUM VITAE

     Name:                                      Natasa SKALKO-BASNET

    Date of birth:                            27. 11. 1963.

    Sex:                                          female

    Nationality:                               Croatian

    Marital status:                           married, one child

    Language ability:                       Croatian, English, German, basic Norwegian

     

                            Education and Professional Qualification

    1986 B. Pharm at Faculty of Pharmacy and Biochemistry, University of Zagreb, CROATIA

                Thesis: The influence of the shampoo properties on the condition of the hair,           supervisor Prof. Dr. M. Cajkovac

     1987    State examination for registered pharmacist

     1990 M Sc in Pharmaceutical Sciences at Faculty of Pharmacy and Biochemistry, University of Zagreb, CROATIA

    Thesis: Liposomes with clindamycin hydrochloride: characterization and application in medical cosmetology, supervisor Prof. Dr. I. Jalsenjak

     1995 PhD at The School of Pharmacy, University of London, U.K

    PhD Thesis: The effect of microfluidization on liposomal surface protein: characterization and immunological studies, supervisor Prof. Dr. G. Gregoriadis

     1999 University "Habilitation" as required for Professorship at the Faculty of Pharmacy and Biochemistry, University of Zagreb, CROATIA

                Subject: Novel drug delivery systems

     

                            Professional Experience

    1986-1987       1 year training in a retail pharmacy, hospital pharmacy and Center for Drug Registration, Zagreb, Croatia; as required for registration for pharmacists

    1987-1990       Master student and teaching associate at the Department of Pharmaceutics, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia,

    1990-1995       University assistant at the Department of Pharmaceutics, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia

    1995-1998       University assistant (lecturer) at the Department of Pharmaceutics, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia

    1998-1999       Higher university assistant (senior lecturer) at the Department of Pharmaceutics, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia

    1999                Professor at the Department of Pharmaceutics, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia

    2001-2008       Professor at The School of Pharmaceutical and Biomedical Sciences, Pokhara University, Nepal; 2004-2008 also Program Director

    April 2008-present, Professor at the Department of Pharmacy, University of Tromso, Norway

    November 2008-July 2009, Head of Section for Pharmaceutics and Biopharmaceutics, Department of Pharmacy, University of Tromsø, Norway

    August 2009-present, Head of Drug Transport and Delivery Research Group, Department of Pharmacy, University of Tromsø, Norway

     

                            International research experience

    United Kingdom

    1990-1991 6 months as a visiting researcher at Centre for Drug Delivery Research, The School of Pharmacy, University of London

                The research subject: Liposomes with covalently coupled ligands                               supervisor Prof. Dr. G. Gregoriadis; financed by Croatian Ministry of Science

    1991-1994 PhD student at The School of Pharmacy, University of London; PhD scholarship awarded by Overseas Research Scheme Program and University of London

     

    Germany

    1992 1 month as a visiting researcher at LS Pharmazeutische Technologie, Pharmazeutishes Institut, University of Freiburg

                The research subject: Characterization of liposomal size by electron microscopy,                             supervisor Dr. M. Brandl; financed by German/English Exchange Program

    1996 2 months as a visiting researcher at LS Pharmazeutische Technologie, Pharmazeutisches Institut, University of Freiburg

    The research subject: The application of surface-conjugated protein in oligonucleotides therapy,

    supervisor Prof. Dr. R. Schubert, financed by Deutsche Akademische Austausch Dienst

    1997-1998 Alexander von Humboldt Foundation Fellow at LS Pharmazeutische Technologie, Pharmazeutisches Institut, University of Freiburg

    The research subject: Liposomes in gene delivery, supervisor Prof. Dr. R. Schubert

     

    The Netherlands

    1993 6 months as a visiting researcher at Department of Pharmaceutical Technology, Leiden/Amsterdam Center for Drug Research, University f Leiden

    The research subject: Characterization of liposomes with surface linked proteins by freeze-fracture-, cryo-electron microscopy and small angle X-ray scattering techniques,

    supervisor Prof. Dr. J. Bouwstra, The research was part of PhD and financed by British Council

    1994 1 month as a visiting researcher at the same laboratory, completing the experiments

     

    Japan

    1999-2000 Science Promotion Officer (Visiting Scientist), Pharmacology Department, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University

                The research subject: Liposomes in gene delivery to the brain

     

    Nepal

    2001-2008 Professor at the School of Pharmaceutical and Biomedical Sciences, Pokhara University

    2004–2008Program Director at the School of Pharmaceutical and Biomedical Sciences, Pokhara University