Do the distribution of blod cells increase the risk of Venous thrombosis?
Findings from K. G. Jebsen TREC suggests that high red blood cell distribution width (RDW) is a risk factor of Venous thromboembolism (VTE), and that RDW is a predictor of all-cause mortality in VTE-patients.
VTE is a major cause of morbidity and mortality, and the cause is unknown in up to 50% of all cases.
The impact of red cell distribution width (RDW) on risk of incident and recurrent VTE, and case-fatality, was investigated in a prospective study of 26 223 participants from the general population.
Participants with RDW in the highest quartile had 50 % higher risk of an incident VTE than those in the lowest quartile. Among the VTE-patients, the risk of all-cause mortality was 30% higher for those in the highest RDW-quartile compared to those in the other quartiles.
The article is published in Thrombosis and Haemostasis
Reference: Ellingsen TS, Lappegard J, Skjelbakken T, Braekkan SK, Hansen JB. Red cell distribution width is associated with incident venous thromboembolism (VTE) and case-fatality after VTE in a general population. Thromb Haemost. 2014;112(6).
Last updated: 31.10.2014 09:24