The 180 °N project is funded by Tromsø Research Foundation and Trond Mohn Foundation, both based on donations from Trond Mohn.
The 180 °N project is a new national research collaboration led by Universities and University Hospitals in Tromsø, Trondheim and Bergen. Stavanger University Hospital also participates as a partner in one of the projects. The 180 °N project aims to develop methods for various cancer diseases and neurological disorders, and to improve patient stratification and personalized treatment. The research program starts in 2019 and will last until 2024.
Towards the collaborative goals, the Bergen project focuses on the development of radioactive tracers, Tromsø on preclinical testing, and Trondheim on clinical trials. A close cooperation network in the fields of tracer development, pharmacology, chemistry, (radiation) oncology, (radiation) biology, nuclear medicine, immunology, drug development and machine learning are established. State-of-the-art imaging diagnostic equipment is also funded by private gifts from Trond Mohn to the University Hospitals in the three cities. This allows method and routine transfer between institutions, and that the projects can reinforce each other with knowledge and data from their focus fields.
Tromsø project: Targeting tumor microenvironment Boosting PET-based diagnostics and therapies
The project in Tromsø, led by Assoc. Prof. Rune Sundset, will test the innovative nuclear medicines in vitro and in vivo at the Preclinical Core Facility with the advanced infrastructure in nuclear medicine and radiation biology. Moreover, in order to improve quantification and to monitor therapy-induced changes, novel machine learning methods will be developed and applied to the imaging data. This will be further developed as a clinical tool to facilitate treatment selection and monitoring in routine clinical application. The Coastal Cooperation, with its unique infrastructure and merged experience, will push forward the development of imaging agents, radiotheranostics and patient-specific nuclear therapies.
Work packages (WP) of the Coastal Cooperation Tromsø project